Cholesterol 7-alpha-Hydroxylase [cholesterol-7-alfa-hydroxylasa]
- Terms
-
cholesterol-7-alfa-hydroxyláza
cholesterol-7-hydroxylasa
cholesterol-7-hydroxyláza
CYP7
CYP7A
cytochrom P-450 7
-
Cholesterol 7-alpha-Monooxygenase
Cholesterol 7alpha-Hydroxylase
Cholesterol-7-Hydroxylase
CYP 7
CYP 7A
CYP7
CYP7A
Cytochrome P-450 CYP7
Cytochrome P450 7
A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.
- DUI
- D002790 MeSH Browser
- CUI
- M0004276
- CAS
- Cholesterol,NADPH:oxygen oxidoreductase (7 alpha-hydroxylating)
- Previous indexing
- Cholesterol (1974); Steroid Hydroxylases (1974)
- History note
- 2003 (1975)
- Public note
- 2003; see CHOLESTEROL 7 ALPHA-MONOOXYGENASE 1997-2002, see CHOLESTEROL-7-HYDROXYLASE 1991-1996, see STEROID HYDROXYLASES 1975-1990
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AN
- analysis 1
- AI
- antagonists & inhibitors
- BI
- biosynthesis 1
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects 1
- EC
- economics
- GE
- genetics 11
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 8
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
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