A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)

DUI

D020110 MeSH Prohlížeč

CUI

M0029848

CAS

Guanidine, N''-cyano-N-4-pyridinyl-N'-(1,2,2-trimethylpropylmonohydrate), (+-)-

Předchozí užití

Guanidines (1983-1998); Pyridines (1980-1982)

Historická pozn.

99; use PINACIDIL (NM) 1980-98

Veřejná pozn.

99; PINACIDIL was indexed under GUANIDINES 1983-98 & PYRIDINES 1980-82