Receptor, trkA [receptor trkA]
- Terms
-
gp140(c-TRK)
neurotrofický receptor typ 1 - tyrosinkinasa
protoonkogenní protein trk
receptor NTRK1
-
c-trk Protein
gp140 c-trk
gp140(c-TRK)
Neurotrophic Tyrosine Kinase Receptor Type 1
NTRK1 Receptor
p140-trkA
Proto-Oncogene Products c-trk
Proto-Oncogene Protein trk
Receptor, Neurotrophic Tyrosine Kinase Type 1
trk Proto-Oncogene Protein
trk1 Transforming Tryrosine Kinase
trkA Receptor
A protein-tyrosine kinase receptor that is specific for NERVE GROWTH FACTOR; NEUROTROPHIN 3; neurotrophin 4, neurotrophin 5. It plays a crucial role in pain sensation and thermoregulation in humans. Gene mutations that cause loss of receptor function are associated with CONGENITAL INSENSITIVITY TO PAIN WITH ANHIDROSIS, while gene rearrangements that activate the protein-tyrosine kinase function are associated with tumorigenesis.
- DUI
- D020917 MeSH Browser
- CUI
- M0328268
- Previous indexing
- Receptors, Nerve Growth Factor (1994-1999); Receptor Protein-Tyrosine Kinases (1994-1999); Proto-Oncogene Proteins (1990-1999)
- History note
- 2000; use RECEPTOR, TYPE 1 NEUROTROPHIC TYROSINE KINASE(NM) 1990-1999
- Public note
- 2000; PROTO-ONCOGENE PROTEIN TRK (now RECEPTOR, TYPE 1 NEUROTROPHIC TYROSINE KINASE) was indexed under PROTO-ONCOGENE PROTEINS 1990-1999, RECEPTOR PROTEIN-TYROSINE KINASE 1994-1999 & RECEPTORS, NERVE GROWTH FACTOR 1994-1999
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors 2
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 11
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 5
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 2
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
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NTRK1 protein, human Chemical MeSH Browser
tyrosine receptor kinase A Ig2 Chemical MeSH Browser