Polyadenylation [polyadenylace]
The addition of a tail of polyadenylic acid (POLY A) to the 3' end of mRNA (RNA, MESSENGER). Polyadenylation involves recognizing the processing site signal, (AAUAAA), and cleaving of the mRNA to create a 3' OH terminal end to which poly A polymerase (POLYNUCLEOTIDE ADENYLYLTRANSFERASE) adds 60-200 adenylate residues. The 3' end processing of some messenger RNAs, such as histone mRNA, is carried out by a different process that does not include the addition of poly A as described here.
- DUI
- D026723 MeSH Browser
- CUI
- M0378712
- Previous indexing
- Poly A/metabolism (1975-2001); RNA, Messenger/metabolism (1974-2001)
- History note
- 2002
- Public note
- 2002
Allowable subheadings