RNA Interference [RNA interference]

topical
248
Terms

ko-suprese
kosuprese
posttranskripční umlčení genů
posttranskripční umlčování genů
RNAi
umlčení RNA
umlčování RNA

 

Co-Suppression
Cosuppression
Gene Silencing, Post-Transcriptional
Post-Transcriptional Gene Silencing
Posttranscriptional Gene Silencing
RNA Silencing
RNAi

Persistent link   https://www.medvik.cz/link/D034622
Definition

A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.

DUI
D034622 MeSH Browser
CUI
M0405879
History note
2003
Public note
2003

Allowable subheadings

DE
drug effects 9
IM
immunology 10
PH
physiology 19
RE
radiation effects 1

G Phenomena and Processes
G01 Physical Phenomena 77
G02 Chemical Phenomena 307
G03 Metabolic Phenomena obsolete
G03 Metabolism 1 197
G04 Cell Physiological Phenomena 515
G05 Genetic Phenomena 135
G05.308 Gene Expression Regulation 1 073
G05.308.203 Epigenesis, Genetic 375
G05.308.203.374 Gene Silencing 129
G05.308.203.374.394 CRISPR-Cas Systems 83
G05.308.203.374.790 RNA Interference 248
G06 Microbiological Phenomena 96
G07 Physiological Phenomena 176
G08 Reproductive and Urinary Physiological Phenomena 18
G09 Circulatory and Respiratory Physiological Phenomena 94
G10 Digestive System and Oral Physiological Phenomena 4
G11 Musculoskeletal and Neural Physiological Phenomena 17
G12 Immune System Phenomena 249
G13 Integumentary System Physiological Phenomena 14
G14 Ocular Physiological Phenomena 148
G15 Plant Physiological Phenomena 158
G16 Biological Phenomena 130
G17 Mathematical Concepts 66

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