cytochrom-B(5)-reduktasa [Cytochrome-B(5) Reductase] tematický
- Termíny
-
cytochrom-B(5)-reduktáza
cytochrom-B5-reduktáza
methemoglobinreduktasa
methemoglobinreduktáza
NADH-cytochrom-B5-reduktáza
-
Methemoglobin Reductase
NADH Cytochrome B5 Reductase
NADH Methemoglobin Reductase
NADH-Cytochrome B5 Reductase
NADH-Ferrihemoglobin Reductase
A FLAVOPROTEIN oxidoreductase that occurs both as a soluble enzyme and a membrane-bound enzyme due to ALTERNATIVE SPLICING of a single mRNA. The soluble form is present mainly in ERYTHROCYTES and is involved in the reduction of METHEMOGLOBIN. The membrane-bound form of the enzyme is found primarily in the ENDOPLASMIC RETICULUM and outer mitochondrial membrane, where it participates in the desaturation of FATTY ACIDS; CHOLESTEROL biosynthesis and drug metabolism. A deficiency in the enzyme can result in METHEMOGLOBINEMIA.
- Anotace
- /defic: consider also METHEMOGLOBINEMIA
- DUI
- D042966
- CUI
- M0073097
- RN
- EC 1.6.2.2
- Předchozí užití
- Oxidoreductases (1973-1974); Cytochrome Reductases (1975-2003); NADH, NADPH Oxidoreductases (1975-1990)
- Historická pozn.
- 2004; use CYTOCHROME B(5) REDUCTASE (NM) 1980-2003
- Veřejná pozn.
- 2004; CYTOCHROME B(5)REDUCTASE was indexed under CYTOCHROME REDUCTASES 1975-2003 & under OXIDOREDUCTASES 1973-1974; for METHEMOGLOBIN REDUCTASE see METHEMOGLOBIN REDUCTASE 1991-2003, see NADH, NADPH OXIDOREDUCTASES 1975-1990
Povolená podhesla
- AN
- analýza 0
- AI
- antagonisté a inhibitory 0
- AD
- aplikace a dávkování 0
- BI
- biosyntéza 0
- CS
- chemická syntéza 0
- CH
- chemie 0
- HI
- dějiny 0
- EC
- ekonomika 0
- PK
- farmakokinetika 0
- PD
- farmakologie 0
- PH
- fyziologie 0
- GE
- genetika 2
- IM
- imunologie 1
- IP
- izolace a purifikace 0
- CL
- klasifikace 0
- BL
- krev 0
- ME
- metabolismus 3
- UR
- moč 0
- CF
- mozkomíšní mok 0
- DF
- nedostatek 1
- ST
- normy 0
- PO
- otrava 0
- AE
- škodlivé účinky 0
- TU
- terapeutické užití 0
- TO
- toxicita 0
- DE
- účinky léků 0
- RE
- účinky záření 0
- UL
- ultrastruktura 0
- SD
- zásobování a distribuce 0
D08.811 enzymy
D08.811.682 oxidoreduktasy
D08.811.682.608 NADH, NADPH oxidoreduktasy
D08.811.682.608.191 cytochromreduktasy
D08.811.682.608.191.237 cytochrom-B(5)-reduktasa
D08.811.682.608.191.500 NADPH-cytochrom c-reduktasa
D12 aminokyseliny, peptidy a proteiny
D12.776 proteiny
D12.776.331 flavoproteiny
D12.776.331.049 acetolaktátsynthasa
D12.776.331.099 acyl-CoA-dehydrogenasa
D12.776.331.102 acyl-CoA-dehydrogenasa s dlouhým řetězcem
D12.776.331.149 acyl-CoA-oxidasa
D12.776.331.161 faktor vyvolávající apoptózu
D12.776.331.174 butyryl-CoA-dehydrogenasa
D12.776.331.180 kryptochromy
D12.776.331.186 cytochrom-B(5)-reduktasa
D12.776.331.192 dihydrolipoamiddehydrogenasa
D12.776.331.199 flavoproteiny přenášející elektrony
D12.776.331.400 flavodoxin
D12.776.331.737 glutamátsynthasa (NADH)
D12.776.331.775 methylentetrahydrofolátreduktasa (NADPH2)
D12.776.331.887 NADH-dehydrogenasa
D12.776.331.894 NADPH-oxidasy
D12.776.331.899 nitrátreduktasa (NADH)
D12.776.331.901 nitrátreduktasa (NAD(P)H)
D12.776.331.911 nitrátreduktasa (NADPH)
D12.776.331.915 retinaldehydrogenasa
D12.776.331.943 sarkosinoxidasa
D12.776.331.971 thioredoxin-disulfidreduktasa