1-Alkyl-2-acetylglycerophosphocholine Esterase [1-alkyl-2-acetylglycerofosfocholinesterasa]
- Terms
-
1-alkyl-2-acetylglycerofosfocholinesteráza
acetylhydrolasa IB destičkového aktivačního faktoru
acetylhydroláza destičkového aktivačního faktoru
acetylhydroláza faktoru aktivujícího destičky
acetylhydroláza IB destičkového aktivačního faktoru
acetylhydroláza PAF
fosfolipáza A2 asociovaná s lipoproteiny
hydroláza destičkového aktivačního faktoru
Lp-PLA2
PAF-acetylhydrolasa
PAF-acetylhydroláza
-
Lipoprotein-Associated Phospholipase A(2)
Lipoprotein-Associated Phospholipase A2
Lp-PLA(2)
Lp-PLA2
PAF 2-Acetylhydrolase
PAF 2-Acylhydrolase
PAF Acetylhydrolase
PAF Acetylhydrolase II
Platelet-activating Factor Acetylhydrolase IB
Platelet-Activating Factor Hydrolase
A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA.
- Annotation
- /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS
- DUI
- D043203 MeSH Browser
- CUI
- M0118406
- Previous indexing
- Phospholipases (1983-2003)
- History note
- 2004(1983)
- Public note
- 2004; 1-ALKYL-2-ACETYLGLYCEROLPHOSPHOCHOLINE ESTERASE was indexed under PHOSPHOLIPASES A 1983-2003; LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 was indexed under PHOSPHOLIPASES A 2000-2007 & under 1-ALKYL-2-ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE 2007
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects 1
- AN
- analysis 1
- AI
- antagonists & inhibitors 5
- BI
- biosynthesis
- BL
- blood 14
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects 3
- EC
- economics
- GE
- genetics 2
- HI
- history
- IM
- immunology
- IP
- isolation & purification
- ME
- metabolism 3
- PK
- pharmacokinetics
- PD
- pharmacology 1
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
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