DNA-(Apurinic or Apyrimidinic Site) Lyase [DNA-lyasa (apurinová nebo apyrimidinová)]
- Terms
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AP endonukleáza
AP lyáza
AP-endonukleáza
AP-lyáza
apurinová DNA-endonukleasa
DNA-lyáza (apurinová nebo apyrimidinová)
endodeoxyribonukleasa (štěpící apurinové nebo apyrimidinové místo)
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AP Endonuclease
AP Lyase
Apurine-Apyrimidine Endonuclease
Apurinic DNA Endonuclease
Apurinic Endonuclease
DNA Lyase (Apurinic or Apyrimidinic)
Endodeoxyribonuclease (Apurinic or Apyrimidinic)
A DNA repair enzyme that catalyses the excision of ribose residues at apurinic and apyrimidinic DNA sites that can result from the action of DNA GLYCOSYLASES. The enzyme catalyzes a beta-elimination reaction in which the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. This enzyme was previously listed under EC 3.1.25.2.
- DUI
- D043603 MeSH Browser
- CUI
- M0073416
- Previous indexing
- Carbon-Oxygen Lyases (1978-2003)
- History note
- 2004; use DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE (NM) 1980-2003
- Public note
- 2004; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE was indexed under CARBON-OXYGEN LYASES 1996-2003, DEOXYRIBONUCLEASES 1978-1982, ENDODEOXYRIBONUCLEASES 1983-1995, ENDONUCLEASES 1978-1982 & LYASES 1978-1980
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