An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F6 recruits chromatin remodeling factors directly to target gene promoters and lacks the transactivation domain responsible for binding to the retinoblastoma family of tumor suppressors.

Anotace

see SCR for organism-specific terms

DUI

D050701 MeSH Prohlížeč

CUI

M0477187

Předchozí užití

Cell Cycle Proteins (1991-2005); DNA-Binding Proteins (1991-2005); Transcription Factors (1991-2005)

Historická pozn.

2006(2004)

Veřejná pozn.

2006; E2F6 TRANSCRIPTION FACTOR, E2F TRANSCRIPTION FACTOR 6 PROTEIN, & TRANSCRIPTION FACTOR E2F-6 were indexed under DNA-BINDING PROTEINS & TRANSCRIPTIONS FACTORS 2004-2005