An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F6 recruits chromatin remodeling factors directly to target gene promoters and lacks the transactivation domain responsible for binding to the retinoblastoma family of tumor suppressors.

Annotation

see SCR for organism-specific terms

DUI

D050701 MeSH Browser

CUI

M0477187

Previous indexing

Cell Cycle Proteins (1991-2005); DNA-Binding Proteins (1991-2005); Transcription Factors (1991-2005)

History note

2006(2004)

Public note

2006; E2F6 TRANSCRIPTION FACTOR, E2F TRANSCRIPTION FACTOR 6 PROTEIN, & TRANSCRIPTION FACTOR E2F-6 were indexed under DNA-BINDING PROTEINS & TRANSCRIPTIONS FACTORS 2004-2005