Apolipoprotein E4 [apolipoprotein E4]
topical
33
- Terms
-
apo E epsilon 4
apo E-4
apo E4
apoE4
apolipoprotein E-4
-
Apo E epsilon 4
Apo E-4
Apo E4
ApoE4
Apolipoprotein E-4
Persistent link
https://www.medvik.cz/link/D053327
Definition
A major and the second most common isoform of apolipoprotein E. In humans, Apo E4 differs from APOLIPOPROTEIN E3 at only one residue 112 (cysteine is replaced by arginine), and exhibits a lower resistance to denaturation and greater propensity to form folded intermediates. Apo E4 is a risk factor for ALZHEIMER DISEASE and CARDIOVASCULAR DISEASES.
- DUI
- D053327 MeSH Browser
- CUI
- M0108562
- Previous indexing
- Apolipoproteins E (1982-2006)
- History note
- 2007 (1982)
- Public note
- 2007; APOLIPOPROTEIN E-4 was indexed under APOLIPOPROTEINS E 1985-2006 & under APOLIPPROTEINS 1982-1984
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AG
- agonists 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 1
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 30
- HI
- history 0
- IM
- immunology 1
- IP
- isolation & purification 0
- ME
- metabolism 3
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs