Apolipoprotein E4 [apolipoprotein E4]
- Terms
-
apo E epsilon 4
apo E-4
apo E4
apoE4
apolipoprotein E-4
-
Apo E epsilon 4
Apo E-4
Apo E4
ApoE4
Apolipoprotein E-4
A major and the second most common isoform of apolipoprotein E. In humans, Apo E4 differs from APOLIPOPROTEIN E3 at only one residue 112 (cysteine is replaced by arginine), and exhibits a lower resistance to denaturation and greater propensity to form folded intermediates. Apo E4 is a risk factor for ALZHEIMER DISEASE and CARDIOVASCULAR DISEASES.
- DUI
- D053327 MeSH Browser
- CUI
- M0108562
- Previous indexing
- Apolipoproteins E (1982-2006)
- History note
- 2007 (1982)
- Public note
- 2007; APOLIPOPROTEIN E-4 was indexed under APOLIPOPROTEINS E 1985-2006 & under APOLIPPROTEINS 1982-1984
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists
- AN
- analysis
- AI
- antagonists & inhibitors
- BI
- biosynthesis
- BL
- blood 1
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- EC
- economics
- GE
- genetics 30
- HI
- history
- IM
- immunology 1
- IP
- isolation & purification
- ME
- metabolism 3
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
apolipoprotein E4 (Freiburg) Chemical MeSH Browser
apolipoprotein E4 (Philadelphia) Chemical MeSH Browser