A highly dense subclass of the high-density lipoproteins, with particle sizes below 7 nm. They are also known as nascent HDL, composed of a few APOLIPOPROTEIN A-I molecules which are complexed with PHOSPHOLIPIDS. The lipid-poor pre-beta-HDL particles serve as progenitors of HDL3 and then HDL2 after absorption of free cholesterol from cell membranes, cholesterol esterification, and acquisition of apolipoproteins A-II, Cs, and E. Pre-beta-HDL initiate the reverse cholesterol transport process from cells to liver.

DUI

D053442 MeSH Browser

CUI

M0209809

Previous indexing

Lipoproteins, HDL (1990-2006)

History note

2007 (1992)

Public note

2007; PRE-BETA HIGH-DENSITY LIPOPROTEIN was indexed under LIPOPROTEINS, HDL 1992-2006