Apoptotic Protease-Activating Factor 1 [faktor 1 aktivující apoptotickou proteasu]

topical
4
Terms

faktor aktivující Apaf-1 proteasu

 

Apaf-1 Protease-Activating Factor
Apoptotic Peptidase Activating Factor 1

Persistent link   https://www.medvik.cz/link/D053477
Definition

A CARD signaling adaptor protein characterized by an N-terminal CARD DOMAIN and C-terminal WD40 REPEATS. It plays a role in the mitochondria-stimulated apoptosis (APOPTOSIS, INTRINSIC PATHWAY) and binds to CYTOCHROME C in the CYTOSOL to form an APOPTOSOMAL PROTEIN COMPLEX which activates INITIATOR CASPASES such as CASPASE 9.

DUI
D053477 MeSH Browser
CUI
M0279898
History note
2007(1997)
Public note
2007; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 was indexed under INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS 1997-2006 & under PROTEINS 1997-2005

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency 1
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 1
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.644 Peptides 1 383
D12.644.360 Intracellular Signaling Peptides and Proteins 175
D12.644.360.024 Adaptor Proteins, Signal Transducing 182
D12.644.360.024.131 CARD Signaling Adaptor Proteins 7
D12.644.360.024.131.124 Apoptotic Protease-Activating Factor 1 4
D12.644.360.024.131.140 B-Cell CLL-Lymphoma 10 Protein
D12.644.360.024.131.186 CRADD Signaling Adaptor Protein
D12.644.360.024.131.249 Nod1 Signaling Adaptor Protein
D12.644.360.024.131.500 Nod2 Signaling Adaptor Protein 21
D12.644.360.075 Apoptosis Regulatory Proteins 79
D12.644.360.075.358 CARD Signaling Adaptor Proteins 7
D12.644.360.075.358.124 Apoptotic Protease-Activating Factor 1 4
D12.644.360.075.358.140 B-Cell CLL-Lymphoma 10 Protein
D12.644.360.075.358.186 CRADD Signaling Adaptor Protein
D12.644.360.075.358.249 Nod1 Signaling Adaptor Protein
D12.644.360.075.358.500 Nod2 Signaling Adaptor Protein 21
D12.776 Proteins 2 581
D12.776.157 Carrier Proteins 546
D12.776.157.057 Adaptor Proteins, Signal Transducing 182
D12.776.157.057.006 CARD Signaling Adaptor Proteins 7
D12.776.157.057.006.124 Apoptotic Protease-Activating Factor 1 4
D12.776.157.057.006.140 B-Cell CLL-Lymphoma 10 Protein
D12.776.157.057.006.155 Caspase 9 24
D12.776.157.057.006.186 CRADD Signaling Adaptor Protein
D12.776.157.057.006.249 Nod1 Signaling Adaptor Protein
D12.776.157.057.006.500 Nod2 Signaling Adaptor Protein 21
D12.776.157.057.006.750 Receptor-Interacting Protein Serine-Threonine Kinase 2 2
D12.776.476 Intracellular Signaling Peptides and Proteins 175
D12.776.476.024 Adaptor Proteins, Signal Transducing 182
D12.776.476.024.139 CARD Signaling Adaptor Proteins 7
D12.776.476.024.139.124 Apoptotic Protease-Activating Factor 1 4
D12.776.476.024.139.140 B-Cell CLL-Lymphoma 10 Protein
D12.776.476.024.139.155 Caspase 9 24
D12.776.476.024.139.186 CRADD Signaling Adaptor Protein
D12.776.476.024.139.249 Nod1 Signaling Adaptor Protein
D12.776.476.024.139.500 Nod2 Signaling Adaptor Protein 21
D12.776.476.024.139.750 Receptor-Interacting Protein Serine-Threonine Kinase 2 2
D12.776.476.075 Apoptosis Regulatory Proteins 79
D12.776.476.075.358 CARD Signaling Adaptor Proteins 7
D12.776.476.075.358.124 Apoptotic Protease-Activating Factor 1 4
D12.776.476.075.358.140 B-Cell CLL-Lymphoma 10 Protein
D12.776.476.075.358.155 Caspase 9 24
D12.776.476.075.358.186 CRADD Signaling Adaptor Protein
D12.776.476.075.358.249 Nod1 Signaling Adaptor Protein
D12.776.476.075.358.500 Nod2 Signaling Adaptor Protein 21
D12.776.476.075.358.750 Receptor-Interacting Protein Serine-Threonine Kinase 2 2

APAF1 protein, human Chemical MeSH Browser

Apaf1 protein, mouse Chemical MeSH Browser

Apaf1 protein, rat Chemical MeSH Browser

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