Transforming Growth Factor beta1 [transformující růstový faktor beta1]
- Terms
-
TGF beta 1
TGF-beta 1
TGF-beta1
TGF-beta1LAP
-
TGF-beta-1
TGF-beta1
TGF-beta1 Latency-Associated Protein
TGF-beta1LAP
Transforming Growth Factor beta 1 Latency Associated Peptide
Transforming Growth Factor beta I
Transforming Growth Factor-beta1
A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
- DUI
- D053773 MeSH Browser
- CUI
- M0024760
- History note
- 2007(1992)
- Public note
- 2007; TRANSFORMING GROWTH FACTOR BETA1 was indexed under TRANSFORMING GROWTH FACTOR 2000-2006; TRANSFORMING GROWTH FACTOR BETA 1 LATENCY ASSOCIATED PEPTIDE was indexed under TRANSFORMING GROWTH FACTOR 1992-2006; TRANSFORMING GROWTH FACTOR BETA I was indexed under PROTEINS 2005-2006
Combination
- deficiency
- Camurati-Engelmann Syndrome
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects
- AG
- agonists 1
- AN
- analysis 3
- AI
- antagonists & inhibitors 3
- BI
- biosynthesis 3
- BL
- blood 10
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DE
- drug effects 2
- EC
- economics
- GE
- genetics 20
- HI
- history
- IM
- immunology 5
- IP
- isolation & purification 2
- ME
- metabolism 21
- PK
- pharmacokinetics
- PD
- pharmacology 6
- PH
- physiology 1
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 1
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine 1
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