Perforin [perforin]
topical
9
- Terms
-
cytolysin
-
Cytolysin
Lymphocyte Pore-Forming Protein
Perforin 1
Persistent link
https://www.medvik.cz/link/D054353
Definition
A calcium-dependent pore-forming protein synthesized in cytolytic LYMPHOCYTES and sequestered in secretory granules. Upon immunological reaction between a cytolytic lymphocyte and a target cell, perforin is released at the plasma membrane and polymerizes into transmembrane tubules (forming pores) which lead to death of a target cell.
- DUI
- D054353 MeSH Browser
- CUI
- M0133732
- Previous indexing
- Membrane Glycoproteins (1985-2007); Pore Forming Cytotoxic Proteins (1985-2007)
- History note
- 2008
- Public note
- 2008; PERFORIN was indexed under MEMBRANE GLYCOPROTEINS & PORE FORMING CYTOTOXIC PROTEINS 1985-2007
Allowable subheadings
- AD
- administration & dosage 0
- AE
- adverse effects 0
- AG
- agonists 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 1
- CL
- classification 0
- DF
- deficiency 0
- DE
- drug effects 2
- EC
- economics 0
- GE
- genetics 4
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 2
- ME
- metabolism 1
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 1
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs