perforin [Perforin]

tematický
9
Termíny

cytolysin

 

Cytolysin
Lymphocyte Pore-Forming Protein
Perforin 1

Perzistentní odkaz   https://www.medvik.cz/link/D054353
Definice

A calcium-dependent pore-forming protein synthesized in cytolytic LYMPHOCYTES and sequestered in secretory granules. Upon immunological reaction between a cytolytic lymphocyte and a target cell, perforin is released at the plasma membrane and polymerizes into transmembrane tubules (forming pores) which lead to death of a target cell.

DUI
D054353 MeSH Prohlížeč
CUI
M0133732
Předchozí užití
Membrane Glycoproteins (1985-2007); Pore Forming Cytotoxic Proteins (1985-2007)
Historická pozn.
2008
Veřejná pozn.
2008; PERFORIN was indexed under MEMBRANE GLYCOPROTEINS & PORE FORMING CYTOTOXIC PROTEINS 1985-2007