Echinocandins [echinokandiny]
topical
51
- Terms
-
akuleaciny
mulundokandiny
pneumokandiny
-
Aculeacin
Aculeacins
Echinocandin
Mulundocandins
Pneumocandin
Pneumocandins
Persistent link
https://www.medvik.cz/link/D054714
Definition
Cyclic hexapeptides of proline-ornithine-threonine-proline-threonine-serine. The cyclization with a single non-peptide bond can lead them to be incorrectly called DEPSIPEPTIDES, but the echinocandins lack ester links. Antifungal activity is via inhibition of 1,3-beta-glucan synthase production of BETA-GLUCANS.
- DUI
- D054714 MeSH Browser
- CUI
- M0507131
- Previous indexing
- Peptides, Cyclic (1981-2007)
- History note
- 2008
- Public note
- 2008
Allowable subheadings
- AD
- administration & dosage 14
- AE
- adverse effects 7
- AG
- agonists 0
- AN
- analysis 0
- AI
- antagonists & inhibitors 0
- BI
- biosynthesis 1
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 0
- CL
- classification 1
- DF
- deficiency 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 0
- HI
- history 0
- IM
- immunology 0
- IP
- isolation & purification 0
- ME
- metabolism 0
- PK
- pharmacokinetics 4
- PD
- pharmacology 26
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 24
- TO
- toxicity 0
- UR
- urine 0
...
Occurrences in Medvik records
D
Chemicals and Drugs
D12.644.641.243
Cyclotides
D12.644.641.311.750
Micafungin
D12.644.641.850
Tyrothricin