CLOCK Proteins [proteiny CLOCK]

topical
19
Terms

protein CLOCK

 

Circadian Locomotor Output Cycles Kaput Proteins
CLOCK Protein

Persistent link   https://www.medvik.cz/link/D056926
Definition

Basic helix-loop-helix (bHLH) domain-containing proteins that contain intrinsic HISTONE ACETYLTRANSFERASE activity and play important roles in CIRCADIAN RHYTHM regulation. Clock proteins combine with Arntl proteins to form heterodimeric transcription factors that are specific for E-BOX ELEMENTS and stimulate the transcription of several E-box genes that are involved in cyclical regulation. This transcriptional activation also sets into motion a time-dependent feedback loop which in turn down-regulates the expression of clock proteins.

DUI
D056926 MeSH Browser
CUI
M0533475
History note
2010(1997)
Public note
2010; CLOCK PROTEIN (now CLOCK PROTEINS) was indexed under TRANSACTIVATORS 1997-2009

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis 1
BL
blood 1
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 12
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 7
PK
pharmacokinetics
PD
pharmacology
PH
physiology 2
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 554
D08.811.913 Transferases 72
D08.811.913.050 Acyltransferases 169
D08.811.913.050.134 Acetyltransferases 54
D08.811.913.050.134.415 Lysine Acetyltransferases 1
D08.811.913.050.134.415.500 Histone Acetyltransferases 21
D08.811.913.050.134.415.500.049 CLOCK Proteins 19
D08.811.913.050.134.415.500.062 Lysine Acetyltransferase 5
D08.811.913.050.134.415.500.074 N-Terminal Acetyltransferase D 1
D08.811.913.050.134.415.500.100 Nuclear Receptor Coactivator 1 4
D08.811.913.050.134.415.500.150 Nuclear Receptor Coactivator 3 4
D08.811.913.050.134.415.500.575 p300-CBP Transcription Factors 5
D12 Amino Acids, Peptides, and Proteins 16
D12.644 Peptides 1 389
D12.644.360 Intracellular Signaling Peptides and Proteins 175
D12.644.360.138 Circadian Rhythm Signaling Peptides and Proteins 11
D12.644.360.138.049 ARNTL Transcription Factors 15
D12.644.360.138.100 CLOCK Proteins 19
D12.644.360.138.150 Cryptochromes 12
D12.644.360.138.575 Period Circadian Proteins 36
D12.776 Proteins 2 584
D12.776.260 DNA-Binding Proteins 563
D12.776.260.103 Basic Helix-Loop-Helix Transcription Factors 65
D12.776.260.103.249 ARNTL Transcription Factors 15
D12.776.260.103.500 Basic Helix-Loop-Helix Leucine Zipper Transcription Factors 32
D12.776.260.103.562 CLOCK Proteins 19
D12.776.260.103.625 Hypoxia-Inducible Factor 1 21
D12.776.260.103.750 Myogenic Regulatory Factors 6
D12.776.260.103.782 Nuclear Receptor Coactivator 1 4
D12.776.260.103.798 Oligodendrocyte Transcription Factor 2
D12.776.260.103.813 Proto-Oncogene Proteins c-myc 69
D12.776.260.103.829 T-Cell Acute Lymphocytic Leukemia Protein 1
D12.776.260.103.844 Transcription Factor HES-1 2
D12.776.260.103.906 Twist Transcription Factors
D12.776.260.103.937 Upstream Stimulatory Factors
D12.776.476 Intracellular Signaling Peptides and Proteins 175
D12.776.476.156 Circadian Rhythm Signaling Peptides and Proteins 11
D12.776.476.156.100 ARNTL Transcription Factors 15
D12.776.476.156.200 CLOCK Proteins 19
D12.776.476.156.250 Cryptochromes 12
D12.776.476.156.300 Nuclear Receptor Subfamily 1, Group D, Member 1 7
D12.776.476.156.437 Nuclear Receptor Subfamily 1, Group F, Member 1
D12.776.476.156.531 Nuclear Receptor Subfamily 1, Group F, Member 2
D12.776.476.156.625 Period Circadian Proteins 36
D12.776.930 Transcription Factors 734
D12.776.930.125 Basic Helix-Loop-Helix Transcription Factors 65
D12.776.930.125.249 ARNTL Transcription Factors 15
D12.776.930.125.500 Basic Helix-Loop-Helix Leucine Zipper Transcription Factors 32
D12.776.930.125.562 CLOCK Proteins 19
D12.776.930.125.625 Hypoxia-Inducible Factor 1 21
D12.776.930.125.750 Myogenic Regulatory Factors 6
D12.776.930.125.782 Oligodendrocyte Transcription Factor 2
D12.776.930.125.813 Proto-Oncogene Proteins c-myc 69
D12.776.930.125.829 T-Cell Acute Lymphocytic Leukemia Protein 1
D12.776.930.125.844 Transcription Factor HES-1 2
D12.776.930.125.906 Twist Transcription Factors
D12.776.930.125.937 Upstream Stimulatory Factors

CLOCK protein, human Chemical MeSH Browser

Clk protein, Drosophila Chemical MeSH Browser

Clock protein, mouse Chemical MeSH Browser

Clock protein, rat Chemical MeSH Browser

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