A DNA-binding orphan nuclear receptor that negatively regulates expression of ARNTL TRANSCRIPTION FACTORS and plays a role as a regulatory component of the circadian clock system. The Nr1d1 nuclear receptor expression is cyclically-regulated by a feedback loop involving its positive regulation by CLOCK PROTEIN; BMAL1 PROTEIN heterodimers and its negative regulation by CRYPTOCHROME and PERIOD PROTEINS.

DUI

D056953 MeSH Prohlížeč

CUI

M0533600

Předchozí užití

DNA-Binding Proteins (1990-2009); Receptors, Cytoplasmic and Nuclear (1990-2009)

Historická pozn.

2010

Veřejná pozn.

2010