A nuclear co-repressor protein that shows specificity for RETINOIC ACID RECEPTORS and THYROID HORMONE RECEPTORS. The dissociation of this co-repressor from nuclear receptors is generally ligand-dependent, but can also occur by way of its phosphorylation by members of the MAP KINASE SIGNALING SYSTEM. The protein contains two nuclear receptor interaction domains and four repressor domains and is closely-related in structure to NUCLEAR RECEPTOR CO-REPRESSOR 1.

DUI

D056985 MeSH Browser

CUI

M0533724

History note

2010(1995)

Public note

2010; NUCLEAR RECEPTOR CO-REPRESSOR 2 was indexed under DNA-BINDING PROTEINS and REPRESSOR PROTEINS 1995-2009