Single-Chain Antibodies [jednořetězcové protilátky]
- Terms
-
jednořetězcové variabilní fragmenty
scFv protilátky
-
Fv Antibody Fragments, Single-Chain
ScFv Antibodies
Single-Chain Fv
Single-Chain Fv Antibody
Single-Chain Fv Antibody Fragments
Single-Chain Variable Fragment
Single-Chain Variable Fragment Antibodies
Single-Chain Variable Fragment Antibody
Single-Chain Variable Fragments
A form of antibodies consisting only of the variable regions of the heavy and light chains (FV FRAGMENTS), connected by a small linker peptide. They are less immunogenic than complete immunoglobulin and thus have potential therapeutic use.
- DUI
- D057127 MeSH Browser
- CUI
- M0534715
- Previous indexing
- Antibodies or specifics (1990-2009); Immunoglobulin Fragments (1992-2009); Immunoglobulin Variable Region (1993-2009)
- History note
- 2010
- Public note
- 2010
Allowable subheadings
- AD
- administration & dosage 1
- AE
- adverse effects 0
- AN
- analysis 0
- BI
- biosynthesis 0
- BL
- blood 0
- CF
- cerebrospinal fluid 0
- CH
- chemistry 2
- CL
- classification 0
- DE
- drug effects 0
- EC
- economics 0
- GE
- genetics 0
- HI
- history 0
- IM
- immunology 4
- IP
- isolation & purification 0
- ME
- metabolism 1
- PK
- pharmacokinetics 0
- PD
- pharmacology 1
- PH
- physiology 0
- PO
- poisoning 0
- RE
- radiation effects 0
- TU
- therapeutic use 0
- TO
- toxicity 0
- UL
- ultrastructure 0
- UR
- urine 0