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Center for Natural Product Technologi... 1 College of Pharmacy University of Ill... 1 Department of Bioinformatics BiGCaT M... 1 Department of Biology University of F... 1 Department of Pharmaceutical Sciences... 1 Institute for Inorganic and Analytica... 1 Institute of Organic Chemistry and Bi... 1 Institute of Pharmaceutical Sciences ... 1 Leibniz Institute of Freshwater Ecolo... 1 Ontario Institute for Cancer Research... 1 Ronin Institute Montclair United States 1 School of Data Science University of ... 1 School of Pharmaceutical Sciences Uni... 1 University of Glasgow Glasgow United ... 1
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Center for Natural Product Technologi... 1 College of Pharmacy University of Ill... 1 Department of Bioinformatics BiGCaT M... 1 Department of Biology University of F... 1 Department of Pharmaceutical Sciences... 1 Institute for Inorganic and Analytica... 1 Institute of Organic Chemistry and Bi... 1 Institute of Pharmaceutical Sciences ... 1 Leibniz Institute of Freshwater Ecolo... 1 Ontario Institute for Cancer Research... 1 Ronin Institute Montclair United States 1 School of Data Science University of ... 1 School of Pharmaceutical Sciences Uni... 1 University of Glasgow Glasgow United ... 1
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- Rutz, Adriano
- Sorokina, Maria
- Galgonek, Jakub
- Mietchen, Daniel
- Willighagen, Egon
- Gaudry, Arnaud
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Graham, James G
Autor Graham, James G Center for Natural Product Technologies and WHO Collaborating Centre for Traditional Medicine (WHO CC/TRM), Pharmacognosy Institute College of Pharmacy, University of Illinois at Chicago, Chicago, United States Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, United States
- Stephan, Ralf
- Page, Roderic
- Vondrášek, Jiří
Free Medical Journals od 2012
PubMed Central od 2012
Europe PubMed Central od 2012
ProQuest Central od 2012-01-01
Open Access Digital Library od 2012-01-01
Open Access Digital Library od 2013-01-01
Health & Medicine (ProQuest) od 2012-01-01
ROAD: Directory of Open Access Scholarly Resources od 2012
PubMed
35616633
DOI
10.7554/elife.70780
Knihovny.cz E-zdroje
Contemporary bioinformatic and chemoinformatic capabilities hold promise to reshape knowledge management, analysis and interpretation of data in natural products research. Currently, reliance on a disparate set of non-standardized, insular, and specialized databases presents a series of challenges for data access, both within the discipline and for integration and interoperability between related fields. The fundamental elements of exchange are referenced structure-organism pairs that establish relationships between distinct molecular structures and the living organisms from which they were identified. Consolidating and sharing such information via an open platform has strong transformative potential for natural products research and beyond. This is the ultimate goal of the newly established LOTUS initiative, which has now completed the first steps toward the harmonization, curation, validation and open dissemination of 750,000+ referenced structure-organism pairs. LOTUS data is hosted on Wikidata and regularly mirrored on https://lotus.naturalproducts.net. Data sharing within the Wikidata framework broadens data access and interoperability, opening new possibilities for community curation and evolving publication models. Furthermore, embedding LOTUS data into the vast Wikidata knowledge graph will facilitate new biological and chemical insights. The LOTUS initiative represents an important advancement in the design and deployment of a comprehensive and collaborative natural products knowledge base.
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Po ukončení testovacího provozu bude odkaz přesměrován adresu produkční verze portálu Medvik.