The purpose of this study was to evaluate the homogeneity of Polish populations with respect to STRs chosen as core markers of the Polish Forensic National DNA Intelligence Database, and to provide reference allele frequencies and to explore the genetic interrelationship between Poland and neighboring countries. The allele frequency distribution of 10 STRs included in the SGMplus kit was analyzed among 2176 unrelated individuals from 6 regional Polish populations and among 4321 individuals from Germany (three samples), Austria, The Netherlands, Sweden, Czech Republic, Slovakia, Belarus, Ukraine and the Russian Federation (six samples). The statistical approach consisted of AMOVA, calculation of pairwise Rst values and analysis by multidimensional scaling. We found homogeneity of present day Poland and consistent differences between Polish and German populations which contrasted with relative similarities between Russian and German populations. These discrepancies between genetic and geographic distances were confirmed by analysis of an independent data set on Y chromosome STRs. Migrations of Goths, Viking influences, German settlements in the region of Volga river and/or forced population resettlements and other events related to World War II are the historic events which might have caused these finding.
- MeSH
- alely MeSH
- emigrace a imigrace MeSH
- frekvence genu MeSH
- genetické markery MeSH
- haplotypy MeSH
- heterozygot MeSH
- lidé MeSH
- lidský chromozom Y MeSH
- mikrosatelitní repetice genetika MeSH
- populační genetika * MeSH
- populační skupiny genetika MeSH
- soudní genetika * MeSH
- zeměpis MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Běloruská republika MeSH
- Česká republika MeSH
- Německo MeSH
- Nizozemsko MeSH
- Polsko MeSH
- Rakousko MeSH
- Rusko MeSH
- Slovenská republika MeSH
- Švédsko MeSH
- Ukrajina MeSH
Mitochondrial DNA (mtDNA) variability was studied in a sample of 179 individuals representing the Czech population of Western Bohemia. Sequencing of two hypervariable segments, HVS I and HVS II, in combination with screening of coding-region haplogroup-specific RFLP markers revealed that most Czech mtDNAs belong to the common West Eurasian mitochondrial haplogroups (H, pre-V HV*, J, T, U, N1, W, and X). However, about 3% of Czech mtDNAs encompass East Eurasian lineages (A, N9a, D4, M*). A comparative analysis with published data showed that different Slavonic populations in Central and Eastern Europe contain small but marked amounts of East Eurasian mtDNAs. We suggest that the presence of East Eurasian mtDNA haplotypes is not an original feature of the gene pool of the proto-Slavs but rather may be mostly a consequence of admixture with Central Asian nomadic tribes, who migrated into Central and Eastern Europe in the early Middle Ages.
- MeSH
- etnicita MeSH
- frekvence genu * MeSH
- genetická variace * MeSH
- genetické testování MeSH
- haplotypy MeSH
- lidé MeSH
- mitochondriální DNA genetika MeSH
- polymorfismus délky restrikčních fragmentů MeSH
- populační genetika * MeSH
- populační skupiny MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
- východní Evropa MeSH
