Herbal compounds including those already well-established in traditional Chinese medicine have been increasingly tested in the treatment of various diseases. Recent studies have shown that herbal compounds can be of benefit also for pulmonary silicosis as they can diminish changes associated with silica-induced inflammation, fibrosis, and oxidative stress. Due to a lack of effective therapeutic strategies, development of novel approaches which may be introduced particularly in the early stage of the disease, is urgently needed. This review summarizes positive effects of several alternative plant-based drugs in the models of experimental silicosis with a potential for subsequent clinical investigation and use in future.
- MeSH
- antiflogistika škodlivé účinky terapeutické užití MeSH
- antioxidancia terapeutické užití MeSH
- lidé MeSH
- mediátory zánětu metabolismus MeSH
- oxidační stres účinky léků MeSH
- plíce účinky léků metabolismus patologie MeSH
- plicní fibróza farmakoterapie metabolismus patologie MeSH
- reaktivní formy kyslíku metabolismus MeSH
- rostlinné přípravky škodlivé účinky terapeutické užití MeSH
- silikóza farmakoterapie metabolismus patologie MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH