Several authors have attributed the explosive outbreak of gastroenteritis that occurred in Czechoslovakia in 1965 to a toxigenic strain of Vibrio cholerae serogroup O37 based on unverified metadata associated with three particular strains from the American Type Culture Collection. Here, by sequencing the original strain preserved at the Czech National Collection of Type Cultures since 1966, we show that the strain responsible for this outbreak was actually a V. cholerae O5 that lacks the genes encoding the cholera toxin, the toxin-coregulated pilus protein and Vibrio pathogenicity islands present in V. cholerae O37 strains.
- MeSH
- cholera * epidemiologie mikrobiologie dějiny MeSH
- cholerový toxin genetika MeSH
- epidemický výskyt choroby * MeSH
- gastroenteritida * mikrobiologie epidemiologie dějiny MeSH
- genomové ostrovy MeSH
- lidé MeSH
- séroskupina MeSH
- Vibrio cholerae * genetika klasifikace MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- historické články MeSH
- úvodníky MeSH
- Geografické názvy
- Československo MeSH