In an 89-year-old man (FH), who monitored his blood pressure (BP) and heart rate (HR) aroundthe- clock at half-hour intervals for decades (with interruptions) and continued to do so before, during and after cataract surgery, we seek any alterations in the time structure of BP and/or HR in relation to this intervention (even though FH recognized no anxiety himself). First, we look at BP and HR within the individualized range of the subject at the given time by a sequential test, and second by reference to broader standards derived from clinically healthy peers of the same gender and corresponding age. The sequential test applied to detect any abnormalities used an individualized reference standard and found changes hidden in the normal range of peers, while data remained within that range. In the week following successful mid-week surgery, the circadian amplitude of diastolic BP increased above peer limits, a reason for caution in the interpretation of the results during the week of intervention as possibly related to subconscious anxiety about the surgery. If they were so related at all, these abnormalities were exceeded by the pleasure (in retrospect “tension”) associated with preparations of materials for publication at a conference, including this report. Apart from testing for physical or emotional loads (stress), we advocate, for any and all estimations of health more generally, a chronobiologically interpreted ambulatory automatic 7-day/24-hour BP and HR monitoring (C-ABPM) as soon as an appointment for a preoperative or any other health check is made, including cataract surgery.
The aim of the study was to assess the time structure (chronome) of sudden cardiac death (SCD) in Austria. The daily incidence of SCD (ICD-10 I46.1) in Austria was obtained for the 4-year span from Jan 2002 to Dec 2005. Data were available separately for men and women. This data series was analyzed by linear-nonlinear rhythmometry. The major feature is the detection of a cis-half-year that is validated nonlinearly, the estimated period of the cis-half-year is 0.408 year (95% CI: 0.389, 0.426). It is concluded that the chronobiological analysis of sudden cardiac death in Austria showed the variability of total incidence with the period of a cis-half-year.
- MeSH
- chronobiologické jevy genetika MeSH
- financování organizované MeSH
- lidé MeSH
- náhlá srdeční smrt epidemiologie etiologie MeSH
- periodicita MeSH
- statistika jako téma metody MeSH
- výzkumný projekt MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- Research Support, U.S. Gov't, P.H.S. MeSH
- Geografické názvy
- Česká republika MeSH
- Rakousko MeSH
We analyzed cycles with periods, tau, in the range of 0.8-2.0 years, characterizing, mostly during 1999-2003, the incidence of sudden cardiac death (SCD), according to the International Classification of Diseases, 10th revision (ICD10), code I46.1. In the tau range examined, only yearly components could be documented in time series from North Carolina, USA; Tbilisi, Georgia; and Hong Kong, in the latter two locations based on relatively short time series. By contrast, in Minnesota, USA, we found only a component with a longer than (= trans) yearly (transyearly) tau of 1.39 years; the 95% confidence interval (CI) of the tau extended from 1.17 to 1.61 years, falling into the category of transyears (defined as a tau and a 95% CI between 1.0 and 2.0 years, with the limits of the 95% CI of the spectral component's tau overlapping neither of these lengths). During the same span from 1999 to 2003 in Arkansas, USA, a component of about 1-year in length was present, and in addition, one with a tau of 1.69 year with a CI extending from 1.29 to 2.07 years, a far-transyear candidate, far-transyears being defined as having a tau with a CI between 1.20 and 2.0 year, with the CI overlapping neither of these lengths. In the Czech Republic, there was also a calendar-yearly tau and one of 1.76 years. In the latter two geographic/geomagnetic areas, the about-yearly and the longer cycles' amplitudes were of similar prominence. The taus are only candidate transyears; the 95% CIs of their taus overlap the 2-year length. When a series on SCD from 1994 to 2003 from the Czech Republic was analyzed, the 95% CI of the transyear's tau no longer overlapped the 2-year length. Transyears were also found in the Czech Republic for myocardial infarctions (MI), meeting the original transyear definition in both a shorter and a longer series. Moreover, in the 1994-2003 series on MI from the Czech Republic, a near-transyear was also found, meeting the definition of a period with a 95% CI overlapping neither precisely 1.0 year nor 1.2 years, along with a far-transyear, defined as a tau between 1.2 and 2.0 years, again with the 95% CI covering neither of these lengths. Herein, we discuss near- and far-transyears more generally in the light of their background in physics and the concept of reciprocal cyclicities.
- MeSH
- chronobiologické jevy * MeSH
- infarkt myokardu epidemiologie MeSH
- lidé MeSH
- náhlá srdeční smrt epidemiologie MeSH
- sluneční aktivita * MeSH
- zeměpis MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- práce podpořená grantem MeSH
- přednášky MeSH
- Research Support, N.I.H., Extramural MeSH
- Geografické názvy
- Česká republika MeSH
- Gruzie epidemiologie MeSH
- Hongkong epidemiologie MeSH
- Spojené státy americké epidemiologie MeSH
The predictive value of blood pressure (BP), heart rate (HR), and catecholamines in terms of any subsequent development of cardiovascular disease was investigated. Systolic (S) and diastolic (D) BP, HR, epinephrine (E) and norepinephrine (NE) were measured three times a year in 1980, 1984, and 1989 on 20 clinically healthy subjects, 18 patients with 'essential hypertension', and 22 patients with angina pectoris. Of the 22 patients in the latter group, 15 died during a 2-year follow-up (1990-1991). Each individual data series was analyzed by single cosinor to assess the circannual variation. Results were summarized by population-mean cosinor for each group. Parameter tests were used to compare the circannual rhythm characteristics among the different patient groups. A circannual rhythm was invariably demonstrated on a group basis (P < 0.05). Differences in MESOR and/or circannual amplitude were found among the different groups. In particular, patients with angina pectoris who will die within the 2-year follow-up differ in terms of their E and NE from all other patient groups, a difference already detected at the beginning of the study, more than 10 years before they die. A similar separation is not achieved in terms of BP or HR.
- MeSH
- adrenalin krev MeSH
- financování organizované MeSH
- hypertenze patofyziologie MeSH
- kardiovaskulární nemoci krev mortalita patofyziologie MeSH
- katecholaminy krev MeSH
- lidé středního věku MeSH
- lidé MeSH
- následné studie MeSH
- noradrenalin krev MeSH
- prediktivní hodnota testů MeSH
- roční období MeSH
- shluková analýza MeSH
- srdeční frekvence fyziologie MeSH
- ukazatele zdravotního stavu MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- MeSH
- Aspirin aplikace a dávkování terapeutické užití MeSH
- benzimidazoly terapeutické užití MeSH
- blokátory receptoru 1 pro angiotenzin II aplikace a dávkování terapeutické užití MeSH
- cirkadiánní rytmus fyziologie MeSH
- dospělí MeSH
- finanční podpora výzkumu jako téma MeSH
- hypertenze farmakoterapie patofyziologie MeSH
- krevní tlak genetika MeSH
- lidé středního věku MeSH
- lidé MeSH
- následné studie MeSH
- srdeční frekvence fyziologie účinky léků MeSH
- výsledek terapie MeSH
- vztah mezi dávkou a účinkem léčiva MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- MeSH
- astronomie MeSH
- chronobiologické jevy genetika MeSH
- cirkadiánní rytmus fyziologie MeSH
- finanční podpora výzkumu jako téma MeSH
- kardiovaskulární fyziologické jevy MeSH
- lidé MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- přehledy MeSH
- MeSH
- chronoterapie metody využití MeSH
- cirkadiánní rytmus fyziologie MeSH
- finanční podpora výzkumu jako téma MeSH
- hypertenze etiologie klasifikace MeSH
- iatrogenní nemoci MeSH
- lidé MeSH
- senioři MeSH
- sotalol terapeutické užití MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- Publikační typ
- kazuistiky MeSH
