Four novel bile acid ethyl amides were synthetized using a well-known method. All the four compounds were characterized by IR, SEM, and X-ray crystal analyses. In addition, the cytotoxicity of the compounds was tested. Two of the prepared compounds formed organogels. Lithocholic acid derivative 1 formed hydrogels as 1% and 2% (w/v) in four different aqueous solutions. This is very intriguing regarding possible uses in biomedicine.
- MeSH
- amidy chemie MeSH
- biokompatibilní materiály chemická syntéza chemie toxicita MeSH
- buňky 3T3 MeSH
- hydrogely chemie MeSH
- kyselina lithocholová chemická syntéza chemie toxicita MeSH
- molekulární konformace MeSH
- molekulární modely MeSH
- myši MeSH
- voda chemie MeSH
- zvířata MeSH
- Check Tag
- myši MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
