BACKGROUND: Hypertension is one of the most prevalent chronic non-communicable diseases and affects more than 60% of individuals over 60 years of age. Additionally, hypertension is a prominent risk factor for the development of cardiovascular diseases (CVDs). Human body composition is both the result and predictor of an individual's health status, and hypertension has consistently been shown to be more prevalent among obese individuals. In the current study, we focussed on the association between body composition parameters and hypertension occurrence. METHODS: Data from KardioVize 2030, a population-based study (n = 1988), was used to determine the association between the body composition parameters related to both fat and water content with hypertension. Body composition was assessed using the direct segmental multi-frequency bioelectrical impedance analysis method (DSM-BIA). RESULTS: Using logistic regression modelling we found that the majority of hypertension incidence could be determined by body fat and water content, as hypertension occurrence was positively correlated with increased fat-related body composition parameters and water content. Specifically, results from this study demonstrate that increased intracellular fluid was positively associated with higher hypertension incidence in men (14%) and women (16%). CONCLUSION: Body composition reflects the occurrence of hypertension and may serve as a novel therapeutic goal that can be easily implemented in the clinical setting using DSM-BIA.

• MeSH
• antropometrie metody   MeSH
• elektrická impedance MeSH
• hypertenze * diagnóza   epidemiologie   MeSH
• index tělesné hmotnosti MeSH
• lidé středního věku MeSH
• lidé MeSH
• obezita epidemiologie   MeSH
• senioři MeSH
• složení těla * MeSH
• voda MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH

Pulse wave velocity is a commonly used parameter for evaluating arterial stiffness and the overall condition of the cardiovascular system. The main goal of this study was to establish a methodology to test and validate multichannel bioimpedance as a suitable method for whole-body evaluations of pulse waves. We set the proximal location over the left carotid artery and eight distal locations on both the upper and lower limbs. In this way, it was possible to simultaneously evaluate pulse wave velocity (PWV) in the upper and lower limbs and in the limbs via four extra PWV measurements. Data were acquired from a statistical group of 220 healthy subjects who were divided into three age groups. The data were then analysed. We found a significant dependency of aortic PWV on age in those values measured using the left carotid as the proximal. PWV values in the upper and lower limbs were found to have no significant dependency on age. In addition, the PWV in the left femoral artery shows comparable values to published already carotid-femoral values. Those findings prove the reliability of whole-body multichannel bioimpedance for pulse wave velocity evaluation and provide reference values for whole-body PWV measurement.

• MeSH
• analýza pulzové vlny * metody   MeSH
• arteriae carotides MeSH
• dolní končetina MeSH
• lidé MeSH
• reprodukovatelnost výsledků MeSH
• stárnutí * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH

The main goal of this study was to make a comparison of aortic flow timing obtained by PW Doppler in four aortic sections with timing of - dZ/dt max obtained by bioimpedance measurement in nine locations on the thorax and neck. This knowledge is essential for determination of which bioimpedance channel could be used as a proximal for evaluation of pulse wave velocity (PWV) from the beginning of the ascending aorta or another aortic section. Time intervals between the Doppler flow and bioimpedance information (- dZ/dt max) were compared. It was found that the channel located on the left part of the neck is the most suitable as a proximal bioimpedance channel which corresponds to the aortic arch. This match is obtained with regard to the value of the time difference as well as inter-subject stability. This channel can be used as a proximal for evaluation of pulse wave velocity from the aortic arch to the desired distal target place in the body when distance between measured parts is known. The data from 35 volunteers with adequate signal quality were analyzed. Graphical abstract ᅟ.

• MeSH
• analýza pulzové vlny metody   MeSH
• aorta diagnostické zobrazování   fyziologie   MeSH
• časové faktory MeSH
• dospělí MeSH
• lidé MeSH
• pletyzmografie impedanční metody   MeSH
• ultrasonografie dopplerovská metody   MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• srovnávací studie MeSH

PURPOSE: The aim of this proof-of-concept study is to introduce new high-dynamic ECG technique with potential to detect temporal-spatial distribution of ventricular electrical depolarization and to assess the level of ventricular dyssynchrony. METHODS: 5-kHz 12-lead ECG data was collected. The amplitude envelopes of the QRS were computed in an ultra-high frequency band of 500-1000 Hz and were averaged (UHFQRS). UHFQRS V lead maps were compiled, and numerical descriptor identifying ventricular dyssynchrony (UHFDYS) was detected. RESULTS: An electrical UHFQRS maps describe the ventricular dyssynchrony distribution in resolution of milliseconds and correlate with strain rate results obtained by speckle tracking echocardiography. The effect of biventricular stimulation is demonstrated by the UHFQRS morphology and by the UHFDYS descriptor in selected examples. CONCLUSIONS: UHFQRS offers a new and simple technique for assessing electrical activation patterns in ventricular dyssynchrony with a temporal-spatial resolution that cannot be obtained by processing standard surface ECG. The main clinical potential of UHFQRS lies in the identification of differences in electrical activation among CRT candidates and detection of improvements in electrical synchrony in patients with biventricular pacing.

• MeSH
• dospělí MeSH
• dysfunkce levé srdeční komory diagnostické zobrazování   terapie   MeSH
• echokardiografie trojrozměrná metody   MeSH
• elektrokardiografie metody   MeSH
• interpretace obrazu počítačem * MeSH
• lidé středního věku MeSH
• lidé MeSH
• remodelace komor fyziologie   MeSH
• senioři MeSH
• srdeční resynchronizační terapie metody   MeSH
• stupeň závažnosti nemoci MeSH
• výsledek terapie MeSH
• vzorkové studie MeSH
• Check Tag
• dospělí MeSH
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH

• Konspekt
• Lékařské vědy. Lékařství

• Klíčová slova
• předpisy právní, zdravotnictví,
• Publikační typ
• příručky MeSH

Široký výběr zákonů a vyhlášek týkajících se zdravotnictví. Příručka poskytuje základní orientaci v jednotlivých právních předpisech.

• MeSH
• zákonodárství jako téma MeSH
• zákonodárství lékařské MeSH
• Publikační typ
• příručky MeSH
• sbírky MeSH
• Geografické názvy
• Česká republika MeSH

• Konspekt
• Lékařské vědy. Lékařství
• NLK Obory
• právo, zákonodárství
• NLK Publikační typ
• zákony