Thirty seven strains of Escherichia coli isolated from the urine of patients with acute symptomatic urinary tract infection were examined for siderophore production: hydroxamate (aerobactin) and phenolate (enterochelin). All the strains were found to produce varying amounts of enterochelin. With the chemical assay, 24.3% strains were aerobactin producers, while 43.2% were positive in the bio-assay. All the aerobactin producers carried the aerobactin receptor on their surface. Attempts to correlate siderophore production with growth in minimal and iron-depleted medium showed that there was a positive quantitative correlation between enterochelin production and growth of organisms under iron depletion. Aerobactin production failed to give an additional advantage of growth to strains producing enterochelin.
- MeSH
- chelátory železa metabolismus MeSH
- enterochelin metabolismus MeSH
- Escherichia coli účinky léků růst a vývoj izolace a purifikace MeSH
- infekce močového ústrojí mikrobiologie MeSH
- infekce vyvolané Escherichia coli mikrobiologie MeSH
- kyseliny hydroxamové metabolismus MeSH
- lidé MeSH
- proteiny vnější bakteriální membrány * MeSH
- receptory imunologické analýza MeSH
- serin analogy a deriváty MeSH
- siderofory MeSH
- železo metabolismus farmakologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- srovnávací studie MeSH
