- MeSH
- časné pohybování metody MeSH
- kardiovaskulární chirurgické výkony * rehabilitace MeSH
- kardiovaskulární detrénovanost MeSH
- kardiovaskulární rehabilitace * metody využití MeSH
- komorbidita MeSH
- lázně MeSH
- lidé MeSH
- pohybová aktivita MeSH
- pooperační péče * metody ošetřování využití MeSH
- statistika jako téma MeSH
- sternotomie ošetřování MeSH
- věkové faktory MeSH
- životní styl MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- přehledy MeSH
Microgravity or simulated microgravity induces acute and chronic cardiovascular responses, whose mechanism is pivotal for understanding of physiological adaptation and pathophysiological consequences. We investigated hemodynamic responses of conscious Wistar rats to 45? head-down tilt (HDT) for 7 days. Arterial blood pressure (BP) was recorded by telemetry. Heart rate (HR), spectral properties and the spontaneous baroreflex sensitivity (sBRS) were calculated. Head-up tilt (HUT) was applied for 2 h before and after HDT to assess the degree of any possible cardiovascular deconditioning. Horizontal control BP and HR were 112.5+/-2.8 mmHg and 344.7+/-10 bpm, respectively. HDT elicited an elevation in BP and HR by 8.3 % and 8.8 %, respectively, in less than 1 h. These elevations in BP and HR were maintained for 2 and 3 days, respectively, and then normalized. Heart rate variability was unchanged, while sBRS was permanently reduced from the beginning of HDT (1.01+/-0.08 vs. 0.74+/-0.05 ms/mmHg). HUT tests before and after HDT resulted in BP elevations (6.9 vs. 11.6 %) and sBRS reduction (0.44 vs. 0.37 ms/mmHg), respectively. The pressor response during the post-HDT HUT test was accompanied by tachycardia (13.7 %). In conclusion, chronic HDT does not lead to symptoms of cardiovascular deconditioning. However the depressed sBRS and tachycardic response seen during the post-HDT HUT test may indicate disturbances in cardiovascular control.
- MeSH
- ambulantní monitorování krevního tlaku MeSH
- autonomní nervový systém patofyziologie MeSH
- baroreflex MeSH
- časové faktory MeSH
- cirkadiánní rytmus MeSH
- elektrokardiografie ambulantní MeSH
- financování organizované MeSH
- fyziologická adaptace MeSH
- hmotnost plodu MeSH
- kardiovaskulární detrénovanost MeSH
- krevní tlak MeSH
- krysa rodu rattus MeSH
- modely u zvířat MeSH
- pití MeSH
- pohybová aktivita MeSH
- postura těla MeSH
- potkani Wistar MeSH
- přijímání potravy MeSH
- simulace stavu beztíže MeSH
- srdeční frekvence MeSH
- telemetrie MeSH
- tělesná teplota MeSH
- Trendelenburgova poloha MeSH
- závrať patofyziologie prevence a kontrola MeSH
- zvířata MeSH
- Check Tag
- krysa rodu rattus MeSH
- mužské pohlaví MeSH
- zvířata MeSH
The high level of the long lasting acceleration with both an extensive gradient of the acceleration onset and vector alterations belong to the flight specificity in a cockpit of agile aircraft with high manoeuvring capabilities. In these cases the so-called push-pull (PP) effect has its particular significance. This means the tolerance decrease to the plus gravitational acceleration turns up after an exposure to the microgravity on the acceleration level between zero and +0.8 Gz or after previous action of negative acceleration values. The resulting activation of the sympathicus during plus gravitational acceleration process is up to several seconds behind time and pilot's performance is reduced. At the same time both an impairment of the threshold of the vision failure and G-LOC occur. The gravitational acceleration fatigue effect escalates, too.
- MeSH
- abdominální dekomprese MeSH
- časové faktory MeSH
- fyziologická adaptace MeSH
- kardiovaskulární detrénovanost MeSH
- krevní tlak MeSH
- letecké a kosmické lékařství MeSH
- lidé MeSH
- simulace stavu beztíže MeSH
- srdce inervace MeSH
- srdeční frekvence MeSH
- sympatický nervový systém fyziologie MeSH
- zrychlení MeSH
- Check Tag
- lidé MeSH
- MeSH
- balneologie MeSH
- kardiovaskulární detrénovanost fyziologie MeSH
- lidé MeSH
- Check Tag
- lidé MeSH
