Aims: The purpose of this study is to evaluate an Altmetric analysis of the 50 most cited refractive surgery articles in Ophthalmology journals and to compare them with traditional metrics. Methods: The term "refractive surgery" was searched, using a time filter between 2010-2020 in the Web of Science core collection database. The 50 most cited articles between 2010 and 2020 were recorded. Descriptive statistics were performed. The Spearman correlation test was used to evaluate the correlation between traditional metrics and Altmetrics. Results: The Altmetric scores of the top 50 articles ranged from 0 to 25, and the median Altmetric score was 4. The citation numbers of the 50 articles ranged from 83 to 523, and the median citation number was 119.5. The most cited article topic was "Toric Intraocular Lens"; the topics with the highest Altmetric scores were "Toric Intraocular Lens" and "Trifocal Intraocular Lens". There was no significant correlation between Altmetric scores and number of citations. There was a weak correlation between Altmetric scores and the average citation per year. Conclusion: The Altmetric score is insufficient, compared with traditional metrics, to show the scientific value of articles on refractive surgery. Altmetrics can be used to supplement traditional metrics.
- MeSH
- Jaw * diagnostic imaging MeSH
- Image Interpretation, Computer-Assisted instrumentation MeSH
- Humans MeSH
- Patient Care Planning MeSH
- Cone-Beam Computed Tomography * MeSH
- Image Processing, Computer-Assisted instrumentation MeSH
- Dental Care organization & administration MeSH
- Information Storage and Retrieval methods MeSH
- Check Tag
- Humans MeSH
Závěrečná práce NCONZO
1 svazek : grafy, tabulky ; 30 cm + 1 CD
- MeSH
- Electronic Data Processing MeSH
- Medical Records Systems, Computerized MeSH
- Documentation methods standards MeSH
- Electronic Health Records MeSH
- Allied Health Occupations MeSH
- Attitude to Computers MeSH
- Surveys and Questionnaires MeSH
- Data Collection methods MeSH
- Information Storage and Retrieval methods MeSH
- Health Workforce MeSH
- Conspectus
- Lékařské vědy. Lékařství
- Teorie systémů. Automatické systémy. Informační systémy. Kybernetika
- NML Publication type
- závěrečné zprávy
Introduction: Effective coping mechanisms and available support systems are essential to managing the disease and maintaining the mental health of women with breast cancer. It has been found that spirituality and religion can be an important supportive element in coping with cancer and its consequences. Aim: To analyse spiritual and religious (s/r) interventions provided by health care professionals to breast cancer patients, and their relationship to physical health, psychosocial, and spiritual outcomes. Methods: Integrative literature review of systematic literature reviews and/or meta-analysis was chosen. PubMed and Web of Science databases for the period 2013-2023 after entering the keywords "spiritual, religious, existential, positive psychology, mindfulness, interventions, breast cancer, cancer" in English were searched. Results: The review included 13 systematic reviews and/or meta-analyses (SRMA). Effect of mindfulness intervention was most frequently analysed. S/r interventions significantly associated with improvements in spiritual and existential well-being, quality of life and personal well-being, hope, optimism, cognitive functions and reductions of anxiety, depression, hopelessness, stress, and fatigue. Two SRMA found that s/r interventions were associated with improvements in cortisol levels, inflammatory cytokine activity, and lymphocyte function. Conclusion: The analysed studies showed that s/r interventions are associated with improved biological, psychosocial and spiritual outcomes, which supports the application of these interventions in clinical practice.
- MeSH
- Complementary Therapies classification methods MeSH
- Quality of Life MeSH
- Humans MeSH
- Religion and Psychology MeSH
- Breast Neoplasms * psychology therapy MeSH
- Review Literature as Topic MeSH
- Psychotherapy methods MeSH
- Spiritual Therapies * classification methods MeSH
- Statistics as Topic MeSH
- Information Storage and Retrieval methods statistics & numerical data MeSH
- Mindfulness methods MeSH
- Check Tag
- Humans MeSH
- Female MeSH
- Publication type
- Review MeSH
Paracetamol (acetaminofen) je od 80. let 20. století jedním z nejoblíbenějších analgetik a antipyretik, které lze užít i u osob, které ostatní analgetika netolerují. Stal se tak jedním z nejužívanějších léků vůbec. Každá mince má dvě strany, tou odvrácenou u paracetamolu je, že předávkování vede k poškození jater, popřípadě ledvin. V rozvinutém světě jsou intoxikace paracetamolem jednou z nejčastějších příčin akutního jaterního selhání. Ačkoliv se hepatotoxicita paracetamolu dostává do povědomí lidí, případů předávkování v České republice podle dotazů na Toxikologické informační středisko (TIS) přibývá. V letech 2020–2022 poskytl TIS celkem 1 712 konzultací u pacientů předávkovaných paracetamolem, což představovalo 6,5 % všech dotazů na léky. Za toxickou dávku se považuje množství větší než 200 mg/kg tělesné hmotnosti nebo více než 10 g. Efektivní, bezpečnou a levnou léčbou je antidotum N-acetylcystein. Doporučení na jeho dávkování se mění. O indikaci rozhoduje také hladina paracetamolu v séru, stanovena nejdříve za 4 hodiny po požití tablet. Hlavním cílem této práce je popsat aktuální doporučený postup při intoxikaci paracetamolem. Při včasné terapii je N-acetylcystein vysoce účinným antidotem a hepatocelulární i renální léze je reverzibilní.
Paracetamol (acetaminophen) has been one of the most popular analgesics and antipyretics since the 1980s, which can be used even by people who cannot tolerate other analgesics. It thus became one of the most widely used medicines ever. Every coin has two sides, the flip side of paracetamol is that an overdose leads to damage of the liver or kidneys. In the developed world, paracetamol intoxication is one of the most common causes of acute liver failure. Although the hepatotoxicity of paracetamol is becoming known to people, overdose cases in the Czech Republic are increasing according to inquiries to the Toxicology Information Center (TIC). In 2020–2022, TIC provided a total of 1,712 consultations for paracetamol overdose patients, which represented 6.5% of all drug inquiries. An amount greater than 200 mg/kg of body weight, or more than 10 g, is considered as a toxic dose. An effective, safe, and inexpensive treatment is the antidote N-acetylcysteine. Recommendations for its dosage vary. The indication is also determined by the level of paracetamol in the serum, collected no earlier than 4 hours after taking the tablets. The main message of this work is to describe the current recommended procedure for paracetamol intoxication. With early therapy, N-acetylcysteine is a highly effective antidote, and both hepatocellular and renal lesions are reversible.
- MeSH
- Acetylcysteine administration & dosage MeSH
- Hospitalization MeSH
- Humans MeSH
- Acetaminophen * poisoning toxicity MeSH
- Suicide, Attempted statistics & numerical data MeSH
- Drug Overdose * drug therapy physiopathology pathology therapy MeSH
- Statistics as Topic MeSH
- Information Storage and Retrieval methods MeSH
- Check Tag
- Humans MeSH
- Publication type
- Review MeSH
- Geographicals
- Czech Republic MeSH
[Accidental dimetindene intoxications in children]
Dimetinden je sedativní antihistaminikum indikované k symptomatické léčbě kašle, běžného nachlazení a kopřivky u dětí. Údaje o toxicitě jsou velmi omezené a neexistuje shoda o dávce, od níž mají být děti hospitalizovány. Podle dotazů Toxikologického informačního střediska (TIS) v letech 2010–2022 se v 95 % případů intoxikovaly děti, jen ve zlomku případů dospělí (5 %). Tento počet konzultací narůstá. Při studiu 100 propouštěcích zpráv z hospitalizací dětí v letech 2020–2022 bylo zjištěno, že až do dávky 0,25 mg/kg tělesné hmotnosti byly děti asymptomatické a do dávky 0,50 mg/kg se vyskytly jen lehké příznaky. Děti byly v 98 % případů hospitalizovány maximálně 24 hodin a jejich stav nevyžadoval léčbu. Podle těchto předběžných výsledků se prognóza náhodných intoxikací dimetindenem u dětí jeví jako dobrá. Při překročení dávky 0,50 mg/kg nebo při pochybnostech však doporučujeme vždy konzultovat TIS.
Dimetindene is a sedative antihistamine indicated for the symptomatic treatment of cough, common cold and urticaria in children. Toxicity data are very limited and there is no consensus on the dose at which children require hospitalization. According to inquiries to Toxicology Information Center (TIC) in the years 2010– 2022, the children were intoxicated in 95% of cases, adults in only a fraction of cases (5%). The number of consultations is increasing. In a study of 100 discharge reports from hospitalizations of children in 2020–2022, it was found that up to a dose of 0.25 mg/kg of body weight, children were asymptomatic, and up to a dose of 0.50 mg/kg, only mild symptoms occurred. In 98% of cases, the children were hospitalized for a maximum of 24 hours and their condition did not require treatment. According to these preliminary results, the prognosis of accidental dimetinden intoxications in children appears to be good. However, if a dose of 0.50 mg/kg is exceeded or in case of doubt, we recommend always consulting TIC.