• Keywords
• kofferdam,
• MeSH
• Latex Hypersensitivity * drug therapy   therapy   MeSH
• Betamethasone pharmacology   therapeutic use   MeSH
• Dimethindene pharmacology   therapeutic use   MeSH
• Rubber Dams adverse effects   MeSH
• Skin Tests methods   utilization   MeSH
• Humans MeSH
• Young Adult MeSH
• Serologic Tests methods   utilization   MeSH
• Treatment Outcome MeSH
• Dentistry, Operative MeSH
• Check Tag
• Humans MeSH
• Young Adult MeSH
• Male MeSH
• Publication type
• Case Reports MeSH

• Keywords
• Cefprozil,
• MeSH
• Cephalosporins * adverse effects   MeSH
• Edema MeSH
• Immunologic Tests utilization   MeSH
• Skin Tests utilization   MeSH
• Drug Hypersensitivity * diagnosis   physiopathology   MeSH
• Young Adult MeSH
• Drug-Related Side Effects and Adverse Reactions MeSH
• Pruritus MeSH
• Treatment Outcome MeSH
• Check Tag
• Young Adult MeSH
• Male MeSH
• Publication type
• Case Reports MeSH

• MeSH
• Histamine Antagonists pharmacology   therapeutic use   MeSH
• Desensitization, Immunologic methods   MeSH
• Immunoglobulin E analysis   blood   MeSH
• Clinical Laboratory Techniques MeSH
• Skin Tests methods   utilization   MeSH
• Humans MeSH
• Rhinitis, Allergic, Seasonal * diagnosis   drug therapy   MeSH
• Check Tag
• Humans MeSH
• Publication type
• Review MeSH

Možnost rychlého a předvídatelného zrušení neuromuskulární blokády navozené rokuroniem či vekuroniem vede ke stále častějšímu použití sugammadexu v klinické praxi. Jeví se jako bezpečné a dobře tolerované léčivo, které je dostupné v zemích Evropské unie i mimo ni. Na našem pracovišti jsme zaznamenali případ závažné anafylaktické reakce po jeho podání, manifestující se těžkým kardiovaskulárním kolapsem. Vzniklá situace vyžadovala okamžité zahájení tekutinové a farmakologické resuscitace. Naší kazuistikou chceme připomenout, že i v zásadě bezpečné léčivo, jako je sugammadex, může způsobit život ohrožující komplikace.

The possibility of rapid and predictable reversal of neuromuscular blockade induced by rocuronium or vecuronium leads to more frequent use of sugammadex in clinical practice. Sugammadex seems to be a safe and well tolerated medicament, which is available throughout the European Union. We noted a case of serious anaphylactic reaction after the administration of sugammadex, manifested by cardiovascular collapse. The situation required immediate initiation of fluid and pharmacological resuscitation. With this case report we would like to illustrate that even a generally safe medicament such as sugammadex may cause serious life-threatening complications.

• MeSH
• Anaphylaxis * etiology   therapy   MeSH
• gamma-Cyclodextrins * adverse effects   MeSH
• Hypotension ethnology   therapy   MeSH
• Skin Tests methods   utilization   MeSH
• Humans MeSH
• Neuromuscular Agents adverse effects   MeSH
• Drug-Related Side Effects and Adverse Reactions * therapy   MeSH
• Postoperative Complications MeSH
• Aged MeSH
• Sugammadex MeSH
• Treatment Outcome MeSH
• Check Tag
• Humans MeSH
• Aged MeSH
• Female MeSH
• Publication type
• Case Reports MeSH

• MeSH
• Allergens immunology   isolation & purification   classification   MeSH
• Allergy and Immunology * trends   MeSH
• Fungi immunology   isolation & purification   classification   MeSH
• Immunoglobulin epsilon-Chains immunology   isolation & purification   MeSH
• Immunoglobulins * immunology   isolation & purification   MeSH
• Immunotherapy methods   trends   utilization   MeSH
• Skin Tests methods   trends   utilization   MeSH
• Humans MeSH
• Molecular Medicine * methods   trends   MeSH
• Pollen immunology   classification   adverse effects   MeSH
• Plant Extracts immunology   isolation & purification   adverse effects   MeSH
• Mites immunology   classification   pathogenicity   MeSH
• Serologic Tests methods   trends   utilization   MeSH
• Statistics as Topic MeSH
• Check Tag
• Humans MeSH
• Geographicals
• Czech Republic MeSH

• MeSH
• Allergens * adverse effects   MeSH
• Child MeSH
• Immunologic Tests methods   utilization   MeSH
• Skin Tests methods   utilization   MeSH
• Laryngitis diagnosis   etiology   therapy   MeSH
• Humans MeSH
• Malus adverse effects   MeSH
• Adolescent MeSH
• Daucus carota adverse effects   MeSH
• Food Hypersensitivity * diagnosis   diet therapy   MeSH
• Pollen MeSH
• Treatment Outcome MeSH
• Cross Reactions MeSH
• Check Tag
• Child MeSH
• Humans MeSH
• Adolescent MeSH
• Male MeSH
• Publication type
• Case Reports MeSH

• Keywords
• histaminová intolerance,
• MeSH
• Milk Hypersensitivity * diagnosis   physiopathology   MeSH
• Asthma diagnosis   drug therapy   MeSH
• Histamine immunology   blood   MeSH
• Immunologic Tests utilization   MeSH
• Comorbidity MeSH
• Skin Tests utilization   MeSH
• Humans MeSH
• Adolescent MeSH
• Milk adverse effects   MeSH
• Food Hypersensitivity * diagnosis   physiopathology   MeSH
• Treatment Outcome MeSH
• Check Tag
• Humans MeSH
• Adolescent MeSH
• Female MeSH
• Publication type
• Case Reports MeSH

• MeSH
• Hypersensitivity diagnosis   MeSH
• Histamine Antagonists pharmacology   therapeutic use   MeSH
• Adult MeSH
• Insulin * adverse effects   MeSH
• Clinical Laboratory Techniques MeSH
• Skin Tests utilization   MeSH
• Drug Hypersensitivity * diagnosis   MeSH
• Humans MeSH
• Drug-Related Side Effects and Adverse Reactions diagnosis   MeSH
• Diphtheria-Tetanus-acellular Pertussis Vaccines adverse effects   MeSH
• Treatment Outcome MeSH
• Check Tag
• Adult MeSH
• Humans MeSH
• Female MeSH
• Publication type
• Case Reports MeSH

• Keywords
• Nové vyšetřovací metody - multiplexy,
• MeSH
• Hypersensitivity * diagnosis   epidemiology   etiology   MeSH
• Allergy and Immunology history   organization & administration   trends   MeSH
• Medical History Taking methods   MeSH
• Anti-Allergic Agents therapeutic use   MeSH
• Biological Therapy * methods   trends   utilization   MeSH
• Asthma etiology   prevention & control   therapy   MeSH
• Epigenomics methods   trends   MeSH
• Genetic Predisposition to Disease * epidemiology   genetics   prevention & control   MeSH
• Genome genetics   immunology   MeSH
• Precision Medicine methods   utilization   MeSH
• Skin Tests methods   utilization   MeSH
• Humans MeSH
• Antibodies, Monoclonal economics   therapeutic use   MeSH
• Food Hypersensitivity diagnosis   etiology   therapy   MeSH
• Rhinitis, Allergic, Seasonal diagnosis   etiology   therapy   MeSH
• Statistics as Topic MeSH
• Check Tag
• Humans MeSH
• Publication type
• Interview MeSH

Existuje pouze málo prací zabývajících se vztahem mezi IgE senzibilizací na inhalační alergeny u pacientů s atopickým ekzémem a dalšími projevy atopie. Cílem této studie je u pacientů s atopickým ekzémem zhodnocení závislosti mezi IgE senzibilizací na běžné inhalační alergeny a výskytem bronchiálního astmatu, alergické rýmy a dalších parametrů. U všech pacientů zahrnutých do studie byla vyšetřena senzibilizace na prach, roztoče, zvířecí srst a peří ptáků pomocí kožních prick testů a sérového IgE. Byla hodnocena závislost mezi senzibilizací na tyto inhalační alergeny a výskytem bronchiálního astmatu, alergické rýmy, trváním atopické dermatitidy, rodinnou anamnézou. Vyšetřili jsme 288 pacientů – 90 mužů a 198 žen. Při statistickém zpracování bylo prokázáno, že IgE senzibilizace na sledované inhalační alergeny zvyšuje riziko vzniku bronchiálního astmatu a alergické rýmy. U pacientů se senzibilizací na peří ptáků se vyskytuje významně častěji vznik atopického ekzému po 5. roce života a u těchto pacientů nebyla prokázána souvislost s výskytem pozitivní rodinné anamnézy. Klíčová slova: atopický ekzém – inhalační alergeny – prach – roztoči – srst zvířat – peří ptáků – bronchiální astma – rýma – začátek atopického ekzému – trvání ekzému – rodinná anamnéza

A few reports demonstrate the relationship between IgE sensitization to aeroallergens in atopic dermatitis and other allergic diseases and parameters. The objective of this study is to evaluate, if there is a significant relationship between the sensitization to common aeroallergens in atopic dermatitis patients and the occurrence of asthma bronchiale, rhinitis, and other atopic parameters. Sensitization to dust, mites, animal dander, and bird feather was examined byskin prick test and specific IgE. The relationship of sensitization to these allergens and the occurrence of asthma bronchiale, rhinitis, duration of atopic dermatitis, family history, and onset of atopic dermatitis was evaluated. We examined 288 patients – 90 men and 198 women. According to our results, IgE sensitisation to animal dander, dust and mites may increase the risk of developing asthma or rhinitis. In patients with sensitization on the feathers of birds occurs significantly more frequently the onset of atopic eczema after the 5th year of life and in these patients no relationship to the positive family history of atopy has been found. Key words: atopic dermatitis – inhalant allergy – mites – dust – animal dander – feather – asthma bronchiale – rhinitis – onset of atopic dermatitis – duration of eczema – family history

• MeSH
• Rhinitis, Allergic MeSH
• Hypersensitivity diagnosis   immunology   classification   MeSH
• Dermatitis, Atopic * immunology   MeSH
• Asthma immunology   MeSH
• Adult MeSH
• Immunization MeSH
• Immunoglobulin E * diagnostic use   immunology   MeSH
• Skin Tests * utilization   MeSH
• Humans MeSH
• Adolescent MeSH
• Young Adult MeSH
• Patch Tests utilization   MeSH
• Check Tag
• Adult MeSH
• Humans MeSH
• Adolescent MeSH
• Young Adult MeSH
• Male MeSH
• Female MeSH