- MeSH
- dospělí MeSH
- hormon uvolňující thyreotropin aplikace a dávkování diagnostické užití sekrece MeSH
- hyperprolaktinemie MeSH
- hypotyreóza diagnóza etiologie farmakoterapie MeSH
- lidé MeSH
- prolaktin krev MeSH
- stupeň závažnosti nemoci MeSH
- thyreotropin krev MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- přehledy MeSH
- srovnávací studie MeSH
Extremely immature neonates are threatened during the first days after delivery by many conditions which are due to incomplete development. - A key role is played during the first days of extrauterine life by the incidence and degree of the respiratory distress syndrome (RDS). Its incidence in neonates bom before the completed 32nd week of gestation is very common. Causal treatment of RDS is not known. To overcome it the neonatologist must use in the majority of infants invasive techniques of controlled ventilation which are associated with the risk of further complications such as barotrauma, retinopathy and later the development of bronchopulmonary dysplasia. Attempts to influence intrauterine maturation of the lungs were started in the fifties. As a routine procedure nowadays corticoids are administered antenatally. Their limited effect divert the attention of perinatologists to other substances which could enhance maturation of pulmonary tissue. In human medicine ambroxol was introduced, in animals opiates are tested as well as beta-mimetics, aminophylline. The greatest hopes were aroused by trials with the use of T-hormones. T-hormones have a maturating regulating function in the foetal organism. They have an affinity for pneumocytes and in animal experiments they have a positive effect on surfactant formation. Moreover they act synergically when combined with corticoids. Objective of study: a) to evaluate the safety of the method from the aspect of undesirable side-effects of hormone administration to the mother b) evaluation of hormone levels: TSH, total T4, total T3, TRH and prolactin in maternal serum.
- MeSH
- dexamethason aplikace a dávkování terapeutické užití MeSH
- hormon uvolňující thyreotropin aplikace a dávkování terapeutické užití MeSH
- kombinovaná farmakoterapie MeSH
- komplikace těhotenství MeSH
- lidé MeSH
- novorozenec nedonošený MeSH
- předčasný porod MeSH
- těhotenství MeSH
- Check Tag
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- MeSH
- hormon uvolňující thyreotropin aplikace a dávkování farmakologie MeSH
- hypothalamus fyziologie účinky léků MeSH
- krvácení krev MeSH
- krysa rodu rattus MeSH
- oxytocin krev MeSH
- vasopresiny antagonisté a inhibitory krev MeSH
- zvířata MeSH
- Check Tag
- krysa rodu rattus MeSH
- mužské pohlaví MeSH
- zvířata MeSH
- MeSH
- dospělí MeSH
- hormon uvolňující thyreotropin aplikace a dávkování farmakologie MeSH
- hypotyreóza patofyziologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- senioři MeSH
- thyreotropin sekrece MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- srovnávací studie MeSH