Pronator teres syndrome is characterized by compression of the median nerve, leading to dysfunction of the affected limb. Median nerve entrapment causes paresthesia, changes in sensitivity, and loss of strength in the fingers, in addition to causing loss of hand dexterity. The diagnosis of pronator teres syndrome is complicated, due to its similarity with other neuropathies of the median nerve. So, it is important to emphasize the need for a physical examination together with imaging tests, especially ultrasound, for its correct diagnosis. We report the case of a 28-year-old woman who complained of tingling for ten years in the proximal third of the left forearm at rest that worsens on exertion and weakness if not moving. On physical examination, she has no limitation of movement but refers to a feeling of weakness and numbness in his forearm. Ultrasonography demonstrates compression of the median nerve between the ulnar and humeral heads of the pronator teres muscle, a finding confirmed by magnetic resonance imaging and electroneuromyography. The patient was treated with physiotherapy presenting improvement of symptoms after 45 days.

• MeSH
• Arthrogryposis MeSH
• Adult MeSH
• Electromyography methods   MeSH
• Hereditary Sensory and Motor Neuropathy MeSH
• Humans MeSH
• Magnetic Resonance Imaging * methods   MeSH
• Median Neuropathy diagnosis   MeSH
• Forearm MeSH
• Ultrasonography methods   MeSH
• Nerve Compression Syndromes diagnosis   physiopathology   MeSH
• Check Tag
• Adult MeSH
• Humans MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Case Reports MeSH

BACKGROUND: Hearing impairment is a prevalent clinical feature in Morquio syndrome (mucopolysaccharidosis IVA or MPS IVA) patients, often presenting in diverse forms: conductive, sensorineural, or a combination known as mixed hearing loss. The mixed form entails a blend of both conductive and sensorineural elements, typically exhibiting a progressive trajectory. This scoping review aimed to comprehensively analyze available evidence pertaining to the pathophysiology, classification, epidemiology, and clinical management of hearing loss in individuals with MPS IVA. METHODS: Targeted literature was searched using MEDLINE, Literatura Latino-Americana e do Caribe em Ciências da Saúde, Web of Science, the Cochrane Library, Trip Medical Database, Embase, ScienceDirect, and Google Scholar, with a second search cycle to identify gray literature. A systematic search strategy using Medical Subject Headings keywords was implemented: "Hearing Disorders" OR "Hearing Loss" AND "Mucopolysaccharidosis IV" or "Hearing Disorders" OR "Hearing Loss" AND "Mucopolysaccharidosis IV." The identified bibliography was uploaded to COVIDENCE platform for information management. Articles were screened by 3 independent reviewers following the eligibility criteria. RESULTS: Twenty-seven articles met the inclusion criteria, spanning information from 568 patients across 16 different countries. None of the studies had complete epidemiological information. Only 2 studies provided sufficient data to address the pathophysiology, while 3 addressed management and treatment. Hearing loss was reported in 210 of 568 patients. A total of 19.2% of patients reported recurrent ear infections. None of the studies reported vertigo, tinnitus, or dizziness in the patients. Pure-tone audiometry was the primary test used to diagnose and monitor auditory impairment in patients with Morquio syndrome. CONCLUSIONS: Five hundred sixty-eight patients with MPS IVA were identified, of whom 210 (37%) developed hearing loss, the most common of which was moderate. Despite the lack of information on the diagnosis and management of hearing loss in Morquio syndrome, this study found that approximately one-third of participants exhibited some form of auditory impairment, with the majority of these cases being sensorineural in nature.

• MeSH
• Humans MeSH
• Mucopolysaccharidosis IV * complications   epidemiology   diagnosis   MeSH
• Hearing Loss * epidemiology   diagnosis   etiology   MeSH
• Check Tag
• Humans MeSH
• Publication type
• Journal Article MeSH
• Scoping Review MeSH

Climate change and population growth are putting increasing pressure on global food security. The development of high-yielding varieties for important crops such as wheat is crucial to meet these challenges. The basis for this is extensive exploitation of beneficial genetic variation resting in genebanks around the world. Selecting suitable donor genotypes from the vast number of wheat accessions stored in genebanks is a difficult task and depends critically on the density of information on the performance of individual accessions. Therefore, this study aimed to access phenotypic data from the Czech genebank, storing over 13,000 wheat accessions. We curated and analyzed data on heading date, plant height, and thousand grain weight for more than one-third of all available accessions regenerated across 70 years. The data underwent analysis using a linear mixed model, revealing high quality of curated data with heritability reaching 99%. The raw data, but also derived data such as the best linear unbiased estimations, are now available for the wheat collection of the Czech genebank for research and breeding.

• MeSH
• Phenotype * MeSH
• Genetic Variation MeSH
• Genotype MeSH
• Triticum * genetics   MeSH
• Plant Breeding * MeSH
• Publication type
• Journal Article MeSH
• Geographicals
• Czech Republic MeSH

AIMS: To determine the incidence of children < 2 years old with suspected abusive head trauma, to evaluate usage of dedicated skeletal radiographs and the incidence of clinically occult fractures on dedicated skeletal radiographs. METHODS: This is a retrospective single centre study of children < 2 years old with traumatic brain injury, referred to the University Hospital's Social Services Department between December 31, 2012 and December 31, 2020. Clinical and demographic data was retrieved from medical notes and imaging was reviewed by paediatric radiologists. RESULTS: 26 children (17 males), 2 weeks to 21 months of age (median age 3 months) were included. Eleven children (42%) had traumatic history, fourteen children (54%) had one or more bruises, eighteen children (69%) had abnormal neurological findings. 16 children (62%) had dedicated skeletal radiographs, 7 children (27%) had radiographs of part of the skeleton and 3 children (11%) had no skeletal radiographs. 5 out of 16 children (31%) with dedicated skeletal radiographs had a clinically occult fracture. 15 (83%) of clinically occult fractures had high specificity for abuse. CONCLUSION: The incidence of suspected abusive head trauma in children < 2 years old is low. Clinically occult fractures were detected in one third of children with dedicated skeletal radiographs. The majority of these fractures have high specificity for abuse. Dedicated skeletal imaging is not performed in more than one third of the children and hence fractures may be missed. Efforts should be taken to increase awareness of child abuse imaging protocols.

• MeSH
• Incidence MeSH
• Infant MeSH
• Craniocerebral Trauma diagnostic imaging   epidemiology   MeSH
• Humans MeSH
• Infant, Newborn MeSH
• Radiography * MeSH
• Retrospective Studies MeSH
• Fractures, Closed diagnostic imaging   MeSH
• Child Abuse * MeSH
• Check Tag
• Infant MeSH
• Humans MeSH
• Male MeSH
• Infant, Newborn MeSH
• Female MeSH
• Publication type
• Journal Article MeSH
• Geographicals
• Czech Republic MeSH

Úvod a cíle: Akutní jednostranná vestibulopatie (AUVP) je definována jako akutní periferní vestibulární syndrom bez prokázaní centrálních neurologických nebo audiologických symptomů. Nyní neexistuje jednotný protokol instrumentálních vyšetření pro diagnostiku a sledování pacientů s AUVP. Vestibulární testy poskytují informace v jednotlivých frekvenčních pásmech vestibulookulárního reflexu (VOR), proto cílem naší práce je zhodnotit přínos multifrekvenčního testování VOR při vyšetření pacientů s AUVP. Metodika: Prospektivně byli vyšetřeni 22 pacienti (9 žen a 13 mužů) s diagnózou AUVP. Multifrekvenční testování zahrnovalo vyšetření spontánního nystagmu se zrušením zrakové fixace (SPN), Head shaking test (HST), bitermální vzduchovou kalorickou zkoušku a Video head impulse test (vHIT). První vyšetření proběhlo do 1 týdne od AUVP, kontrolní vyšetření byla provedena z odstupem 3 a 6 měsíců. Při třetím vyšetření byl vyplněn dotazník dizziness handicap inventory (DHI). Výsledky: Rychlost pomalé složky spontánního a indukovaného nystagmu při HST a hodnoty jednostranné slabosti (UW) při kalorické zkoušce se v průběhu sledování snížily se statisticky významným rozdílem (p < 0,05) jak mezi prvním a druhým, tak i mezi druhým a třetím vyšetřením. Na vHIT byl během sledování prokázán statisticky významný narůst gainu jednotlivých kanálků. Disociace výsledků vHIT a kalorické zkoušky byla zjištěna u 22,73 % pacientů při druhém a u 18,18 % pacientů při třetím vyšetření. Byl prokázán statisticky významný rozdíl ve změnách výsledků testů pacientů s různým DHI. Závěr: Multifrekvenční testování VOR poskytuje komplexní přehled o stavu vestibulární funkce, o dynamice zotavení a o klinickém dopadu reziduální vestibulární dysfunkce po AUVP.

Introduction: Acute unilateral vestibulopathy (AUVP) is defined as an acute peripheral vestibular syndrome without evidence of central neurological or audiological symptoms. Currently, there is no uniform instrumental testing protocol for the diagnosis and follow-up of patients with AUVP. Vestibular tests provide information in different frequency bands of the vestibuloocular reflex (VOR); therefore, the aim of our study is to evaluate the contribution of multifrequency VOR testing in the evaluation of patients with AUVP. Methods: 22 patients (9 females and 13 males) with a diagnosis of AUVP were prospectively examined. Multifrequency testing included spontaneous nystagmus with visual fixation cancellation (SPN), Head Shaking Test (HST), bithermal air caloric test, and video Head Impulse Test (vHIT). The first examination was performed within one week of AUVP; follow-up examinations were performed 3 and 6 months apart. On the third examination, the Dizziness handicap inventory (DHI) questionnaire was completed. Results: The rate of the slow component of spontaneous and induced nystagmus during HST and the values of unilateral weakness (UW) during caloric testing decreased during follow-up with a statistically significant difference (P <0.05) between both the first and second and between the second and third examinations. On vHIT, there was a statistically significant increase in the gains of individual channels during follow-up. Dissociation of vHIT and caloric test results was found in 22.73% of patients on the second and 18.18% of patients on the third examination. There was a statistically significant difference in the changes in test results of patients with different DHI. Conclusion: Multifrequency VOR testing provides a comprehensive overview of the status of vestibular function, recovery dynamics, and clinical impact of residual vestibular dysfunction after AUVP.

• Keywords
• akutní jednostranná vestibulopatie,
• MeSH
• Diagnosis, Differential MeSH
• Adult MeSH
• Adrenal Cortex Hormones administration & dosage   pharmacology   therapeutic use   MeSH
• Middle Aged MeSH
• Humans MeSH
• Adolescent MeSH
• Nystagmus, Pathologic diagnosis   etiology   MeSH
• Prospective Studies MeSH
• Head Impulse Test methods   MeSH
• Aged MeSH
• Vestibular Function Tests * classification   methods   MeSH
• Vestibular Neuronitis * diagnostic imaging   diagnosis   classification   MeSH
• Reflex, Vestibulo-Ocular physiology   MeSH
• Check Tag
• Adult MeSH
• Middle Aged MeSH
• Humans MeSH
• Adolescent MeSH
• Male MeSH
• Aged MeSH
• Female MeSH
• Publication type
• Research Support, Non-U.S. Gov't MeSH

During an ichthyoparasitological survey in 2017-2019, six species of acanthocephalans were found among Taiwan's freshwater (Cypriniformes: Xenocyprididae, Cyprinidae) and marine fishes (Scombriformes: Scombridae, Trichiuridae; Anabantiformes: Channidae; Carangaria/misc: Latidae): Micracanthorhynchina dakusuiensis (Harada, 1938), Rhadinorhynchus laterospinosus Amin, Heckmann et Ha, 2011, Pallisentis rexus Wongkham et Whitfield, 1999, Longicollum sp., Bolbosoma vasculosum (Rudolphi, 1819), and one new species, Micracanthorynchina brevelemniscus sp. n. All species are morphologically characterised and illustrated using light and scanning electron microscopy. The finding of R. laterospinosus, P. rexus and B. vasculosum is the first record for these species in Taiwan. Micracanthorhynchina brevelemniscus is similar to Micracanthorhynchina motomurai (Harada, 1935) and M. dakusuiensis in proboscis armature but differs from M. motomurai by larger eggs (53-59 × 15-16 μm vs 40 × 16 μm) and by the number of cement glands (6 vs 4) and from M. dakusuiensis by shorter body length (2.2-2.9 mm vs 4.0 mm in males and 2.9-4.1 mm vs 7.6 mm in females), by the location of the organs of the male reproductive system (from level of the posterior third of the proboscis receptacle in M. brevelemniscus vs in the posterior half of the trunk in M. dakusuiensis), and by length of lemnisci (lemnisci shorter than the proboscis receptacle vs lemnisci longer than the proboscis receptacle). Phylogenetic analyses of almost complete 18S rRNA gene revealed paraphyly of the family Rhadinorhynchidae suggested in previous studies. Micracanthorhynchina dakusuiensis and M. brevelemniscus formed a strongly supported cluster, which formed the earliest diverging branch to the rest of the rhadinorhynchids and transvenids.

• MeSH
• Acanthocephala * anatomy & histology   MeSH
• Phylogeny MeSH
• Helminthiasis, Animal * epidemiology   MeSH
• Cypriniformes * MeSH
• Fish Diseases * epidemiology   MeSH
• Perciformes * MeSH
• Fishes MeSH
• Animals MeSH
• Check Tag
• Male MeSH
• Female MeSH
• Animals MeSH
• Publication type
• Journal Article MeSH
• Geographicals
• Taiwan MeSH

Herein, we describe a case of epidural hematoma associated with the use of a Mayfield head clamp. An 18-year old patient with an upper brainstem tumour causing obstructive hydrocephalus underwent a routine third ventriculostomy, which unexpectedly revealed an intracranial hemorrhage. We outline potential risk factors, propose an algorithm for preventing complications associated with the use of pin-type fixation, and conducted a structured review of the literature to identify similar clinical scenarios.

• Publication type
• Case Reports MeSH

BACKGROUND: To investigate mental health, sleep, and addiction features of young otolaryngologists (YO) according to the mobilization in COVID-19 units at the end of the third European wave of infections. METHODS: A cross-sectional survey was sent to 220 YO of 6 European University hospitals. The following outcomes were evaluated: postgraduate year; age; management of COVID-19 patients; workload; nights on call; stress; Beck depression inventory; Insomnia severity index; sleep and mental health status evolutions throughout pandemic; consumption of alcohol, tobacco, and drugs before and during pandemic. RESULTS: A total of 128 YO completed the evaluations (58.2%). Twenty responders (15.6%) did not manage COVID-19 patients, while 65 (50.8%), 20 (15.6%), and 23 (18%) managed rarely, frequently or daily COVID-19 patients during the pandemic, respectively. The management of COVID-19 patients was associated with increases of workload (p = 0.023) and number of nights on-call (p < 0.001). At the end of the third wave, the depression rates were 34% (N = 31/68) and 57% (N = 34/60) in YO who worked less and more than 50 h weekly, respectively. Sleep disturbance concerned 39% (N = 26/66) and 55% (N = 27/60) of YO who worked less and more than 50 h weekly, respectively. Mobilized YO reported a significant increase of alcohol consumption compared with control group (p = 0.002). Tobacco and drugs consumptions did not evolve. The consumption of alcohol was positively correlated with the number of nights on-call (p = 0.036) and the total hours of work (p = 0.009). CONCLUSIONS: Young otolaryngologists (YO) mobilized in COVID-19 units reported higher hours worked, nights on call, and alcohol consumption compared with others. Future large cohort-studies are needed to confirm our observations.

• MeSH
• COVID-19 * epidemiology   MeSH
• Depression epidemiology   MeSH
• Humans MeSH
• Otolaryngology * MeSH
• Cross-Sectional Studies MeSH
• SARS-CoV-2 MeSH
• Anxiety MeSH
• Health Status MeSH
• Check Tag
• Humans MeSH
• Publication type
• Journal Article MeSH

Úvod: Flexibilní endoskopické vyšetření polykání (FEES) je objektivní dia gnostická metoda určená ke stanovení orofaryngeální dysfagie. Přítomnost poruchy polykání a nastavení optimálního managementu výrazně ovlivňují klinický stav a kvalitu života pacientů. Metodika: V průběhu let 2014–2021 byly prospektivně hodnoceny výsledky vyšetření FEES podle penetračně-aspirační škály u osmi kategorií onemocnění – cévní mozková příhoda, jiná ložisková onemocnění mozku, tumory v oblasti hlavy a krku, neurodegenerativní onemocnění, refl uxní choroby, polyneuropatie spojená s umělou plicní ventilací, operace krční páteře a jiná onemocnění. Výsledky: Celkem bylo na našem pracovišti provedeno 2 601 vyšetření FEES. Ve dvou třetinách ze všech případů byla potvrzena orofaryngeální dysfagie. Nejvyšší výskyt penetrace a aspirace, tj. u více než 70 % vyšetření, byl prokázán u cévních mozkových příhod a jiných ložiskových onemocnění mozku. U jedné čtvrtiny všech vyšetření z celkového souboru byla prokázána tichá aspirace. Závěr: Objektivní vyšetření polykání FEES by mělo být součástí komplexní nemocniční péče o pacienta v riziku dysfagie. Časný záchyt patologie polykání snižuje riziko komplikací spojených s dysfagií. FEES vyšetření je důležitou dia gnostickou metodou v rámci mezioborové spolupráce, nejen u pacientů s onemocněním v ORL oblasti.

Introduction: Flexible endoscopic evaluation of swallowing (FEES) is an objective dia gnostic method designed to assess the oropharyngeal dysphagia. The presence of swallowing disorder and the optimal management settings signifi cantly aff ect patients’ clinical status and quality of life. Methods: From 2014 to 2021, FEES was prospectively evaluated against the penetration-aspiration scale for eight disease categories – stroke, other focal brain lesions, head and neck tumours, neurodegenerative diseases, refl ux diseases, polyneuropathy associated with artifi cial lung ventilation, cervical spine surgery and other diseases. Results: A total of 2,601 FEES examinations were carried out at our workplace. Oropharyngeal dysphagia was confi rmed in two-thirds of all cases. The highest incidence of penetration and aspiration, i.e. in more than 70% of examinations, has been shown in stroke and other focal brain lesions. In one quarter of all examinations in the total set, silent aspiration was demonstrated. Conclusion: The objective examination of swallowing FEES should be part of comprehensive hospital care for a patient at risk of dysphagia. Early detection of swallowing pathology reduces the risk of complications associated with dysphagia. FEES examination is an important dia gnostic method within the framework of interdisciplinary cooperation, not only in patients with diseases in the ENT area.

• MeSH
• Endoscopy, Gastrointestinal MeSH
• Humans MeSH
• Deglutition Disorders * diagnosis   etiology   pathology   MeSH
• Prevalence MeSH
• Prospective Studies MeSH
• Risk Factors MeSH
• Check Tag
• Humans MeSH
• Publication type
• Research Support, Non-U.S. Gov't MeSH