26906976 OR Aerobic mitochondria of parasitic protists Diverse genomes and complex functions Dotaz Zobrazit nápovědu
In this review the main features of the mitochondria of aerobic parasitic protists are discussed. While the best characterized organelles are by far those of kinetoplastid flagellates and Plasmodium, we also consider amoebae Naegleria and Acanthamoeba, a ciliate Ichthyophthirius and related lineages. The simplistic view of the mitochondrion as just a power house of the cell has already been abandoned in multicellular organisms and available data indicate that this also does not apply for protists. We discuss in more details the following mitochondrial features: genomes, post-transcriptional processing, translation, biogenesis of iron-sulfur complexes, heme metabolism and the electron transport chain. Substantial differences in all these core mitochondrial features between lineages are compatible with the view that aerobic protists harbor organelles that are more complex and flexible than previously appreciated.
- MeSH
- editace RNA MeSH
- elektronový transportní řetězec metabolismus MeSH
- genom mikrobiální * MeSH
- hem metabolismus MeSH
- kyslík metabolismus MeSH
- mitochondriální ribozomy metabolismus MeSH
- mitochondrie genetika metabolismus MeSH
- paraziti genetika metabolismus MeSH
- replikace DNA MeSH
- RNA genetika metabolismus MeSH
- síra metabolismus MeSH
- strukturální variace genomu MeSH
- železo metabolismus MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH