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Autor
Ackerman, Jacobo Miranda 1 Ahrends, Robert 1 Aimo, Lucila 1 Alvarez-Jarreta, Jorge 1 Andrews, Robert 1 Andrews, Simon 1 Bridge, Alan 1 Clair, Geremy C 1 Conroy, Matthew J 1 Fahy, Eoin 1 Fedorova, Maria 1 Gaud, Caroline 1 Goracci, Laura 1 Hartler, Jürgen 1 Hoffmann, Nils 1 Jukes, Geoff 1 Kopczyinki, Dominik 1 Korf, Ansgar 1 Kutmon, Martina 1 Lopez-Clavijo, Andrea F 1
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Pracoviště
Babraham Institute Babraham Research ... 1 Biological Science Division Pacific N... 1 Bruker Daltonics GmbH and Co KG Breme... 1 Center for Biotechnology University o... 1 Center of Membrane Biochemistry and L... 1 Department of Analytical Chemistry Un... 1 Department of Bioengineering Universi... 1 Department of Bioinformatics BiGCaT N... 1 Department of Biotechnology and Life ... 1 Department of Chemistry Biology and B... 1 European Molecular Biology Laboratory... 1 Field of Excellence BioHealthe Univer... 1 Graduate School of Medical Life Scien... 1 Institute of Organic Chemistry and Bi... 1 Institute of Parasitology McGill Univ... 1 Institute of Pharmaceutical Sciences ... 1 Maastricht Centre for Systems Biology... 1 Max Planck Institute of Molecular Cel... 1 RIKEN Center for Integrative Medical ... 1 RIKEN Center for Sustainable Resource... 1
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Autor
Ackerman, Jacobo Miranda 1 Ahrends, Robert 1 Aimo, Lucila 1 Alvarez-Jarreta, Jorge 1 Andrews, Robert 1 Andrews, Simon 1 Bridge, Alan 1 Clair, Geremy C 1 Conroy, Matthew J 1 Fahy, Eoin 1 Fedorova, Maria 1 Gaud, Caroline 1 Goracci, Laura 1 Hartler, Jürgen 1 Hoffmann, Nils 1 Jukes, Geoff 1 Kopczyinki, Dominik 1 Korf, Ansgar 1 Kutmon, Martina 1 Lopez-Clavijo, Andrea F 1
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Pracoviště
Babraham Institute Babraham Research ... 1 Biological Science Division Pacific N... 1 Bruker Daltonics GmbH and Co KG Breme... 1 Center for Biotechnology University o... 1 Center of Membrane Biochemistry and L... 1 Department of Analytical Chemistry Un... 1 Department of Bioengineering Universi... 1 Department of Bioinformatics BiGCaT N... 1 Department of Biotechnology and Life ... 1 Department of Chemistry Biology and B... 1 European Molecular Biology Laboratory... 1 Field of Excellence BioHealthe Univer... 1 Graduate School of Medical Life Scien... 1 Institute of Organic Chemistry and Bi... 1 Institute of Parasitology McGill Univ... 1 Institute of Pharmaceutical Sciences ... 1 Maastricht Centre for Systems Biology... 1 Max Planck Institute of Molecular Cel... 1 RIKEN Center for Integrative Medical ... 1 RIKEN Center for Sustainable Resource... 1
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NLK
ProQuest Central
od 2004-10-01 do Před 1 rokem
Health & Medicine (ProQuest)
od 2004-10-01 do Před 1 rokem
PubMed
36543939
DOI
10.1038/s41592-022-01710-0
Knihovny.cz E-zdroje
Progress in mass spectrometry lipidomics has led to a rapid proliferation of studies across biology and biomedicine. These generate extremely large raw datasets requiring sophisticated solutions to support automated data processing. To address this, numerous software tools have been developed and tailored for specific tasks. However, for researchers, deciding which approach best suits their application relies on ad hoc testing, which is inefficient and time consuming. Here we first review the data processing pipeline, summarizing the scope of available tools. Next, to support researchers, LIPID MAPS provides an interactive online portal listing open-access tools with a graphical user interface. This guides users towards appropriate solutions within major areas in data processing, including (1) lipid-oriented databases, (2) mass spectrometry data repositories, (3) analysis of targeted lipidomics datasets, (4) lipid identification and (5) quantification from untargeted lipidomics datasets, (6) statistical analysis and visualization, and (7) data integration solutions. Detailed descriptions of functions and requirements are provided to guide customized data analysis workflows.
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