The aim of this paper was to summarise knowledge of IL-22 involvement in multiple sclerosis (MS) and the possible link between IL-22 and two transcription factors - AHR and c-Maf. The conclusion is that despite numerous studies, the exact role of IL-22 in the pathogenesis of MS is still unknown. The expression and function of c-Maf in MS have not been studied. It seems that the functions of c-Maf and AHR are at least partly connected with IL-22, as both directly or indirectly influence the regulation of IL-22 expression. This possible connection has never been studied in MS.

• MeSH
• adaptorové proteiny signální transdukční fyziologie   MeSH
• interleukiny fyziologie   MeSH
• lidé MeSH
• receptory aromatických uhlovodíků fyziologie   MeSH
• roztroušená skleróza etiologie   MeSH
• transkripční faktory bHLH fyziologie   MeSH
• transkripční faktory fyziologie   MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH