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Autor
Adjemian, Sandy 1 Agostinis, Patrizia 1 Cesano, Alessandra 1 Chan, Timothy A 1 Coukos, George 1 Demaria, Sandra 1 Deutsch, Eric 1 Draganov, Dobrin 1 Edelson, Richard L 1 Formenti, Silvia C 1 Fucikova, Jitka 1 Gabriele, Lucia 1 Gaipl, Udo S 1 Galluzzi, Lorenzo 1 Gameiro, Sofia R 1 Garg, Abhishek D 1 Golden, Encouse 1 Han, Jian 1 Harrington, Kevin J 1 Hemminki, Akseli 1
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Pracoviště
Calidi Biotherapeutics San Diego Cali... 1 Cancer Gene Therapy Group Translation... 1 Candiolo Cancer Institute FPO IRCCS C... 1 Caryl and Israel Englander Institute ... 1 Cell Death Research and Therapy Labor... 1 Center of Clinical Investigations in ... 1 Centre de Recherche du Centre Hospita... 1 Centro de Investigação Translacional ... 1 Comprehensive Cancer Center Helsinki ... 1 Comprehensive Cancer Center Yale Univ... 1 Department of Bioengineering Universi... 1 Department of Biomedical Molecular Bi... 1 Department of Dermatology Yale School... 1 Department of Immunology Charles Univ... 1 Department of Immunology University o... 1 Department of Medical Biology Univers... 1 Department of Medicine Memorial Sloan... 1 Department of Medicine Weill Cornell ... 1 Department of Oncology University of ... 1 Department of Oncology University of ... 1
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Autor
Adjemian, Sandy 1 Agostinis, Patrizia 1 Cesano, Alessandra 1 Chan, Timothy A 1 Coukos, George 1 Demaria, Sandra 1 Deutsch, Eric 1 Draganov, Dobrin 1 Edelson, Richard L 1 Formenti, Silvia C 1 Fucikova, Jitka 1 Gabriele, Lucia 1 Gaipl, Udo S 1 Galluzzi, Lorenzo 1 Gameiro, Sofia R 1 Garg, Abhishek D 1 Golden, Encouse 1 Han, Jian 1 Harrington, Kevin J 1 Hemminki, Akseli 1
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Pracoviště
Calidi Biotherapeutics San Diego Cali... 1 Cancer Gene Therapy Group Translation... 1 Candiolo Cancer Institute FPO IRCCS C... 1 Caryl and Israel Englander Institute ... 1 Cell Death Research and Therapy Labor... 1 Center of Clinical Investigations in ... 1 Centre de Recherche du Centre Hospita... 1 Centro de Investigação Translacional ... 1 Comprehensive Cancer Center Helsinki ... 1 Comprehensive Cancer Center Yale Univ... 1 Department of Bioengineering Universi... 1 Department of Biomedical Molecular Bi... 1 Department of Dermatology Yale School... 1 Department of Immunology Charles Univ... 1 Department of Immunology University o... 1 Department of Medical Biology Univers... 1 Department of Medicine Memorial Sloan... 1 Department of Medicine Weill Cornell ... 1 Department of Oncology University of ... 1 Department of Oncology University of ... 1
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Galluzzi, Lorenzo
Autor Galluzzi, Lorenzo Department of Radiation Oncology, Weill Cornell Medical College, New York City, New York, USA deadoc80@gmail.com Sandra and Edward Meyer Cancer Center, New York City, New York, USA Caryl and Israel Englander Institute for Precision Medicine, New York City, New York, USA Department of Dermatology, Yale School of Medicine, New Haven, Connecticut, USA Université de Paris, Paris, France
- Vitale, Ilio
- Warren, Sarah
- Adjemian, Sandy
- Agostinis, Patrizia
- Martinez, Aitziber Buqué
- Chan, Timothy A
- Coukos, George
- Demaria, Sandra
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Deutsch, Eric
Autor Deutsch, Eric Department of Radiation Oncology, Gustave Roussy Cancer Campus, Villejuif, France INSERM "Molecular Radiotherapy and therapeutic innovation", U1030 Molecular Radiotherapy, Gustave Roussy Cancer Campus, Villejuif, France SIRIC SOCRATES, DHU Torino, Faculté de Medecine, Université Paris-Saclay, Kremlin-Bicêtre, France
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PubMed
32209603
DOI
10.1136/jitc-2019-000337
Knihovny.cz E-zdroje
Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune response associated with immunological memory, provided they display sufficient antigenicity and adjuvanticity. Moreover, multiple intracellular and microenvironmental features determine the propensity of RCD to drive adaptive immunity. Here, we provide an updated operational definition of immunogenic cell death (ICD), discuss the key factors that dictate the ability of dying cells to drive an adaptive immune response, summarize experimental assays that are currently available for the assessment of ICD in vitro and in vivo, and formulate guidelines for their interpretation.
- MeSH
- imunogenní buněčná smrt genetika MeSH
- konsensus MeSH
- lidé MeSH
- molekulární biologie metody MeSH
- směrnice jako téma MeSH
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- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- Research Support, N.I.H., Extramural MeSH
- Research Support, U.S. Gov't, Non-P.H.S. MeSH
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