Diagnostic methods used in the contemporary medical practice consist of a combination of distressing invasive (bronchial biopsy, bronchoalveolar lavage) and semiinvasive (induced sputum technique) methods. Monitoring of specific molecules produced during pathological processes in biological matrices is a relatively new technique which represents an alternative, entirely non-invasive and comfortable method. The principle is based on the quantification of specific substances – "biomarkers", which are considered to be objectively measurable indicators of a physiological/pathological condition of the organism. In contrast with non-specific matrices such as blood plasma (reflecting the state of the whole organism), the exhaled breath condensate is a specific matrix. Concentration levels of biomarkers in the latter matrix point at pathological processes only in the airways and lungs. Typical molecules to be monitored include hydrogen peroxide, leukotrienes, prostaglandins, lipoxins and prostanoids.

• Klíčová slova
• kondenzát vydechovaného vzduchu,
• MeSH
• biologické markery analýza   MeSH
• chronická obstrukční plicní nemoc diagnóza   MeSH
• diagnostické techniky dýchacího ústrojí MeSH
• ELISA MeSH
• hmotnostní spektrometrie MeSH
• kyseliny prostanové analýza   MeSH
• leukotrieny analýza   MeSH
• lidé MeSH
• lipoxiny analýza   MeSH
• metody pro podporu rozhodování MeSH
• prognóza MeSH
• prostaglandiny analýza   MeSH
• vysokoúčinná kapalinová chromatografie MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• práce podpořená grantem MeSH