Q96201169
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Úvod: Podle dostupných pramenů trpí syndromem obstrukční spánkové apnoe (OSAS) ve čtvrté dekádě života 1-5 % ženské populace a více než 90 % žen s OSAS o svém problému neví. Přibližně 15 % obézních těhotných žen má pravděpodobně SAS (Sleep Apnoe Syndrome). Cílem práce je průzkum výskytu OSAS v populaci rizikově těhotných a průzkum souvislosti OSAS s rizikovými faktory pro těhotenství. Charakteristika souboru: Ze 480 sledovaných těhotných bylo zkoumáno 85 a do studie zařazeno 61 rizikově těhotných respondentek. Metody: Statisticky jsme zhodnotili vztah OSAS k hypertenzi, obezitě, preeklamptickým změnám placenty, nízkému pH pupečníkové krve, nízké hladině PlGF ve skupině rizikově těhotných s AHI < 5 a ve skupině s AHI ≥ 5. Výsledky: Ve studovaném souboru byla prokázána významná statistická souvislost výskytu OSAS s gestačním diabetem a obezitou u rizikově těhotných. Nebyla prokázána souvislost s výskytem hypertenze. Pro nízký záchyt respondentek s těmito potížemi nebyla statisticky přínosná hodnocení výskytu histomorfologických preeklamptických změn placenty, nízkého pH pupečníkové krve a nízké hladiny PlGF.
Introduction: According to the available data, OSAS (Obstructive Sleep Apnea Syndrome) occurs in the fourth decade in 1 to 5% of women in the total population, and over 90% of women with OSAS do not know about their problems. Approximately 15% of obese pregnant females are thought to suffer from SAS. The aim of this work is to explore OSAS incidence in high-risk pregnant women and the association of OSAS with risk factors for pregnancy. Material: 85 women of a group of 480 monitored high-risk pregnant females were examined, and 61 of these were involved in this study. Methods: We statistically evaluated the relation between OSAS and hypertension, obesity, preeclamptic placental changes, low pH values of umbilical cord blood, and low PlGF levels in the group of high-risk pregnant women with AHI < 5 and in the group with AHI ≥ 5. Results: In the monitored group there was a statistical significant coherence between OSAS and gestational diabetes and obesity in high-risk gravid women. Surprisingly, an association with hypertension was not found. From a statistical point of view, evaluations of histomorphological preeclamptic placental changes, low pH values of umbilical cord blood and low PlGF levels was not significant for a small number of respondents with these disorders.
- MeSH
- komorbidita MeSH
- obstrukční spánková apnoe * epidemiologie MeSH
- rizikové faktory MeSH
- rizikové těhotenství * MeSH
- těhotenství MeSH
- Check Tag
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
Introduction: Laryngeal cancer is the most frequent cancer in the head and neck area. Approximately one third of patients are treated by total laryngectomy (TL). The rate of the patient's adaptation to new conditions is crucial to the quality of his or her future life. Some patients survive tens of years after this operation. The preparation for TL is a complicated process that affects a patient's cooperation in postsurgical time. The patient is informed of the essence of the disease, treatment possibilities, the process of preoperative preparation, as well as the operation itself. Great emphasis is put on awareness of the postoperative development, the patient's good cooperation, as well as good prognosis of the disease. Losing one's voice and the cosmetic defects caused by the tracheostoma are a great problem for the patient. The aim of this study was to show the main problems that patients after total laryngectomy deal with in common life. Material: In the group, there were 102 patients who had been operated on between 2003 and 2013, 62 of which met the classification criteria. Methods: This prospective study was statistically evaluated. The frequencies of responses were processed in tables. Results: During the early postoperative period, the greatest problem of patients after total laryngectomy is their adaptation to new principles of breathing, which is subsequently followed by the adaptation to a new and different way of communication. The best option for the patient is to communicate using esophageal voice. Only 55% of operated patients use one of the verbal forms of alternative voice communication in their future lives.
