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Autor
Di Giuseppe, Daniela 1 Georgiadis, Stylianos 1 Hellamand, Pasoon 1 Hetland, Merete Lund 1 Jones, Gareth T 1 Kristianslund, Eirik Klami 1 Kvien, Tore K 1 Macfarlane, Gary J 1 Michelsen, Brigitte 1 Nordström, Dan 1 Perdan Pirkmajer, Katja 1 Provan, Sella A 1 Rodrigues, Ana Maria 1 Rotar, Žiga 1 Santos, Maria José 1 Wallman, Johan K 1 Závada, Jakub 1 van der Horst-Bruinsma, Irene 1 Ørnbjerg, Lykke Midtbøll 1 Østergaard, Mikkel 1
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Pracoviště
1 van der Horst Bruinsma MD PhD Rheum... 1 A M Rodrigues MD PhD EpiDoC Unit CEDO... 1 B Michelsen MD PhD Center for Treatme... 1 D Di Giuseppe PhD Clinical Epidemiolo... 1 D Nordström MD PhD Departments of Med... 1 E K Kristianslund MD PhD Center for T... 1 G J Macfarlane MD PhD Aberdeen Centre... 1 G T Jones PhD Aberdeen Centre for Art... 1 J K Wallman MD PhD Department of Clin... 1 J Závada MD PhD Institute of Rheumato... 1 K Perdan Pirkmajer MD Department of R... 1 L M Ørnbjerg MD PhD Copenhagen Center... 1 M J Santos MD PhD Department of Rheum... 1 M L Hetland MD PhD DMSc Copenhagen Ce... 1 M Østergaard MD PhD DMSc Copenhagen C... 1 P Hellamand MD Department of Rheumato... 1 S A Provan MD PhD Center for Treatmen... 1 S Georgiadis PhD Copenhagen Center fo... 1 T K Kvien MD PhD Center for Treatment... 1 Ž Rotar MD PhD Department of Rheumato... 1
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Autor
Di Giuseppe, Daniela 1 Georgiadis, Stylianos 1 Hellamand, Pasoon 1 Hetland, Merete Lund 1 Jones, Gareth T 1 Kristianslund, Eirik Klami 1 Kvien, Tore K 1 Macfarlane, Gary J 1 Michelsen, Brigitte 1 Nordström, Dan 1 Perdan Pirkmajer, Katja 1 Provan, Sella A 1 Rodrigues, Ana Maria 1 Rotar, Žiga 1 Santos, Maria José 1 Wallman, Johan K 1 Závada, Jakub 1 van der Horst-Bruinsma, Irene 1 Ørnbjerg, Lykke Midtbøll 1 Østergaard, Mikkel 1
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Pracoviště
1 van der Horst Bruinsma MD PhD Rheum... 1 A M Rodrigues MD PhD EpiDoC Unit CEDO... 1 B Michelsen MD PhD Center for Treatme... 1 D Di Giuseppe PhD Clinical Epidemiolo... 1 D Nordström MD PhD Departments of Med... 1 E K Kristianslund MD PhD Center for T... 1 G J Macfarlane MD PhD Aberdeen Centre... 1 G T Jones PhD Aberdeen Centre for Art... 1 J K Wallman MD PhD Department of Clin... 1 J Závada MD PhD Institute of Rheumato... 1 K Perdan Pirkmajer MD Department of R... 1 L M Ørnbjerg MD PhD Copenhagen Center... 1 M J Santos MD PhD Department of Rheum... 1 M L Hetland MD PhD DMSc Copenhagen Ce... 1 M Østergaard MD PhD DMSc Copenhagen C... 1 P Hellamand MD Department of Rheumato... 1 S A Provan MD PhD Center for Treatmen... 1 S Georgiadis PhD Copenhagen Center fo... 1 T K Kvien MD PhD Center for Treatment... 1 Ž Rotar MD PhD Department of Rheumato... 1
- Publikační typ
- Kategorie
- Jazyk
- Země
- Časopis/zdroj
- Georgiadis, Stylianos
- Ørnbjerg, Lykke Midtbøll
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Michelsen, Brigitte
Autor Michelsen, Brigitte ORCID B. Michelsen, MD, PhD, Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, and Research Unit, Sørlandet Hospital, Kristiansand, Norway, and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Copenhagen University Hospital Rigshospitalet, Glostrup, Denmark
- Kvien, Tore K
- Di Giuseppe, Daniela
- Wallman, Johan K
- Závada, Jakub
- Provan, Sella A
- Kristianslund, Eirik Klami
- Rodrigues, Ana Maria
PubMed
38621792
DOI
10.3899/jrheum.2023-1217
PII: jrheum.2023-1217
Knihovny.cz E-zdroje
OBJECTIVE: Ankylosing Spondylitis Disease Activity Score based on C-reactive protein (ASDAS-CRP) is recommended over ASDAS based on erythrocyte sedimentation rate (ASDAS-ESR) to assess disease activity in axial spondyloarthritis (axSpA). Although ASDAS-CRP and ASDAS-ESR are not interchangeable, the same disease activity cut-offs are used for both. We aimed to estimate optimal ASDAS-ESR values corresponding to the established ASDAS-CRP cut-offs (1.3, 2.1, and 3.5) and investigate the potential improvement of level of agreement between ASDAS-ESR and ASDAS-CRP disease activity states when applying these estimated cut-offs. METHODS: We used data from patients with axSpA from 9 European registries initiating a tumor necrosis factor inhibitor. ASDAS-ESR cut-offs were estimated using the Youden index. The level of agreement between ASDAS-ESR and ASDAS-CRP disease activity states was compared against each other. RESULTS: In 3664 patients, mean ASDAS-CRP was higher than ASDAS-ESR at both baseline (3.6 and 3.4, respectively) and aggregated follow-up at 6, 12, or 24 months (1.9 and 1.8, respectively). The estimated ASDAS-ESR values corresponding to the established ASDAS-CRP cut-offs were 1.4, 1.9, and 3.3. By applying these cut-offs, the proportion of discordance between disease activity states according to ASDAS-ESR and ASDAS-CRP decreased from 22.93% to 19.81% in baseline data but increased from 27.17% to 28.94% in follow-up data. CONCLUSION: We estimated the optimal ASDAS-ESR values corresponding to the established ASDAS-CRP cut-off values. However, applying the estimated cut-offs did not increase the level of agreement between ASDAS-ESR and ASDAS-CRP disease activity states to a relevant degree. Our findings did not provide evidence to reject the established cut-off values for ASDAS-ESR.
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Po ukončení testovacího provozu bude odkaz přesměrován adresu produkční verze portálu Medvik.