The authors analyze a group of 39 patients with gastric cancer in different thirds of the stomach in relation to the incidence of regional nodal metastases and the preoperative evaluation of the proximal and distal resection line. They recommend lymphadenectomy of all three nodal compartments as they are regularly affected with metastases, and mandatory preoperative microscopic examination of the resection lines.
- MeSH
- dospělí MeSH
- gastrektomie MeSH
- karcinom sekundární chirurgie MeSH
- lidé středního věku MeSH
- lidé MeSH
- lymfadenektomie MeSH
- lymfatické metastázy MeSH
- nádory žaludku patologie chirurgie MeSH
- prospektivní studie MeSH
- senioři MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
The objective of the work was to assess the impact of the shift of gastric cancer in an oral direction in the mediastinal lymph nodes. For this purpose a new miniinvasive lower mediastinoscopy was used in 30 patients. The method is safe and can be used also in other situations. Mediastinal metastases may occur in cancer in the distal and medium third of the stomach. They need not be present when cancer is in the upper third. The shift of gastric carcinoma did not influence the mediastinal nodes.
- MeSH
- břicho MeSH
- dospělí MeSH
- karcinom sekundární chirurgie MeSH
- laparoskopie MeSH
- lidé středního věku MeSH
- lidé MeSH
- lymfadenektomie * MeSH
- lymfatické metastázy MeSH
- lymfatické uzliny anatomie a histologie MeSH
- mediastinoskopie MeSH
- mediastinum MeSH
- nádory žaludku patologie chirurgie MeSH
- senioři MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
The authors analyze a group of 32 patients with thyroid cancer. They always dissect the recurrent nerve and search for the parathyroid glands. They draw attention to the constant course of the branch of the lower thyroid artery beneath the ligament of Berry. In their opinion the basic operation comprises bilateral total lobectomy with cervicocentral lymphadenectomy. In case of scintigraphic, USG or CT evidence of secondaries in the other cervical triangles, they make after some interval a modified cervical dissection. They make a circular resection of the invaded cervical trachea. Peroperative histology makes a so-called single-stage operation possible.
- MeSH
- dospělí MeSH
- karcinom patologie chirurgie MeSH
- lidé středního věku MeSH
- lidé MeSH
- nádory štítné žlázy patologie chirurgie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
An unusual testicular tumour with features of both sex cord tumour with annular tubules and large-cell calcifying Sertoli cell tumour is described. The tumour occurred in a 20-year-old man in the left testis as a 1 cm-measuring well circumscribed solitary lesion. Histologically, it showed sertoliform annular tubules with included eosinophilic nodules as well as isolated large cells and cords to sheets of the cells lying in a sclerosing stroma. A few psammomatous microcalcifications were seen. In contrast to similar cases reported before, the patient did not have any signs of Peutz-Jeghers syndrome, feminization or other complex dysplastic syndromes. The case indicates that tumours of this type may occur in phenotypically normal patients like pure large cell calcifying Sertoli cell tumours or ovarian sex-cord tumours with annular tubules. It further supports a close histogenetic relationship between these two entities.
- MeSH
- dospělí MeSH
- gonadální stromální nádory patologie MeSH
- kalcinóza patologie MeSH
- lidé MeSH
- nádor ze Sertoliho buněk patologie MeSH
- testikulární nádory patologie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- kazuistiky MeSH
We describe four cases of ectopic hamartomatous thymoma with unusual morphological features. In cases 1 and 2 we found a dysplastic glandular component which was often arranged in a cribriform pattern bridging several glandular spaces. In case 2 we found solid adenocarcinomatous areas with infiltrative edges. Case 3 showed widespread smooth muscle differentiation within the spindle epithelial cell component, the presence of multiple clear cell glands which contained a distinct myoepithelial layer and an overall picture which vaguely resembled a sclerosing adenosis of the breast. Case 4 contained frequent foci of multinucleated giant epithelial cells within the markedly cellular spindle cell component: it also showed multiple, hypocellular, myxoid areas containing eosinophilic cords and pearls of squamous cells, and resembled squamous cell carcinoma with a sarcomatoid spindle cell component. We could not find any evidence of a thymic origin or of thymic differentiation in our four cases or in any other reported cases of ectopic hamartomatous thymoma. We believe that ectopic hamartomatous thymomas manifest salivary gland differentiation.
- MeSH
- biologické markery MeSH
- dospělí MeSH
- hamartom metabolismus patologie ultrastruktura MeSH
- imunohistochemie MeSH
- klíční kost MeSH
- lidé MeSH
- nádory hrudníku metabolismus patologie MeSH
- sternum MeSH
- thymom metabolismus patologie ultrastruktura MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- přehledy MeSH
- Názvy látek
- biologické markery MeSH
The authors investigated the prevalence of Helicobacter pylori (H. p.) in atrophic gastritis in the antrum and/or in the corpus of the stomach (groups I-IV), as compared with mucosae without atrophy. Criteria for elimination were age under 50 years, a case-history of the use of antibiotics during the last 6 months and chronic ingestion of alcoholic beverages. Group IV was formed by probands with pernicious anaemia who were divided into sub-group IVa with atrophy of the corpus and sub-group IVb with atrophy of the corpus and antrum. It was revealed that in probands with pernicious anaemia the presence of H. p. is significantly reduced (p < 0.01) when atrophy was present not only in the corpus but also in the antrum. The authors concluded that atrophic changes in the corpus only do not have a significant effect on the presence of H. p. in the antrum. The presence of H. p. is significantly influenced in a negative sense only when atrophic changes, in particular total atrophy, affect the antral mucosa.
- MeSH
- atrofie MeSH
- gastritida atrofická komplikace mikrobiologie patologie MeSH
- Helicobacter pylori * MeSH
- infekce vyvolané Helicobacter pylori * komplikace patologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- perniciózní anemie komplikace prevence a kontrola MeSH
- senioři MeSH
- žaludeční sliznice patologie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
The authors describe a case of relapsing severe haemorrhage from angiodysplasias localized in the small intestine in an eighty-year-old female patient diagnosed only after probatory laparotomy. They discuss the diagnostic possibilities in angiodysplasia of the gastrointestinal tract and how it can be influenced by therapy. Even after resection of the affected portion of the intestine the formation of new angiodysplasias must be foreseen in previously intact areas and those can be the source of further severe haemorrhage.
- MeSH
- angiodysplazie komplikace diagnóza terapie MeSH
- gastrointestinální krvácení diagnóza etiologie terapie MeSH
- lidé MeSH
- nemoci jejuna komplikace diagnóza terapie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- Check Tag
- lidé MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- kazuistiky MeSH
The works is based on a previous investigation published in the journal Vnitrní Lékarství, 36, 1990, 8, pp. 759-762. The authors investigated morphological changes of the gastric mucosa and the presence of Campylobacter pylori (CP) in probands with chronic active surface CP positive antrum gastritis one year after treatment with a bismuth preparation (Bismuth citrate 120 mg per capsule made on prescription) for a one-month period 4 capsules per day. This concerned probands with functional dyspepsia without a history of alcohol intake. After a one-year interval eradication of CP persisted in 8 probands (53.3%); in 7 patients (46.7%) there was a relapse of CP positivity. The authors confirmed that CP and active chronic gastritis are associated. Chronic non-specific inflammatory cellulitis persisted after one year with the same intensity in 17 probands (74%), in 6 it increased by one grade (26%). Improvement or complete recovery of the histological finding was not recorded in any of the patients. In the corpus of the stomach the unaltered finding persisted. Morphological changes were always directly proportional to the presence of CP. Its eradication appears to be causal treatment of chronic active surface CP positive antrum gastritis, one of the groups in the wide spectrum of chronic gastritis.
- MeSH
- bismut terapeutické užití MeSH
- časové faktory MeSH
- chronická nemoc MeSH
- dospělí MeSH
- gastritida farmakoterapie mikrobiologie patologie MeSH
- Helicobacter pylori * MeSH
- kampylobakterové infekce farmakoterapie MeSH
- lidé středního věku MeSH
- lidé MeSH
- žaludeční sliznice patologie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- bismut MeSH
The authors investigated the effect of one month bismuth treatment (Bismuthi citrici 120 mg per capsule), 4 x 120 mg/day, on morphological changes of the gastric mucosa along with the effect on Campylobacter pylori (CP) in a group of 23 probands with histologically verified active superficial CP positive antrum gastritis. The probands suffered only from functional dyspepsia, to eliminate the action of other disease of the digestive tract on chronic gastritis. Complete eradication of CP occurred in 65.2% and disappearance of granulocytic infiltration as a manifestation of activity in 73.9%. The disappearance of activity correlated with the eradication of CP in 88.2. The authors evaluated also the degree of circular nuclear cellulization (grade 1-3). After one-month treatment it was reduced by 1 grade in 56.5% in the antrum, while in the corpus it remained unaltered in the majority. Complete histological normalization of the mucosa was not recorded.
- MeSH
- antacida terapeutické užití MeSH
- chronická nemoc MeSH
- dospělí MeSH
- gastritida farmakoterapie patologie MeSH
- Helicobacter pylori * MeSH
- infekce vyvolané Helicobacter pylori farmakoterapie patologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- organokovové sloučeniny terapeutické užití MeSH
- žaludeční sliznice patologie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- antacida MeSH
- bismuth tripotassium dicitrate MeSH Prohlížeč
- organokovové sloučeniny MeSH
The authors describe the incidence of Crohn's disease at an uncommon site the stomach--in a 40-year-old man. With regard to the steadily increasing incidence of the disease, it is important to consider its presence also in uncommon sites in the gastrointestinal tract. The establishment of the diagnosis must be comprehensive, as even histological examination of endobioptic specimens or resected portions need not be unequivocal from the diagnostic aspect.
- MeSH
- Crohnova nemoc * diagnóza MeSH
- dospělí MeSH
- lidé MeSH
- nemoci žaludku * diagnóza MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- kazuistiky MeSH
