BACKGROUND: Cardiovascular disease is a serious problem increasingly affecting young people worldwide. Cardio-metabolic risk factors include lipid profile parameters and atherogenic index of plasma (AIP), as well as basic anthropometric parameters such as the ratio of waist circumference to height (WHtR). The aim of our study was to determine WHtR. METHOD: WHtR was determined in a group of 500 clinically healthy young people aged 18-25 and, on the basis of measured data, a reference range for WHtR was designed. RESULTS: The average WHtR value for the whole group was 0.45±0.06, with 0.46±0.06 for men, and 0.44±0.06 for women. WHtR values in respondents with all other parameters in normal range were from 0.41 to 0.52 for men and from 0.38 to 0.50 for women. Values are similar to those observed in other studies across diverse world populations. A positive correlation was observed between WHtR and atherogenic indices (AP1, AIP) uric acid levels and lipid profile parameters at p<0.001, with the exception of glucose and HDL. WHtR and HDL were negatively correlated at p<0.001. CONCLUSION: As WHtR can be easily determined, it can be used as another cardio-metabolic risk factor.
- Klíčová slova
- atherogenic parameters, cardio-metabolic risk, lipid profile, waist circumference to height ratio, young people,
- MeSH
- antropometrie metody MeSH
- dospělí MeSH
- hodnocení rizik MeSH
- kardiovaskulární nemoci diagnóza MeSH
- lidé MeSH
- mladiství MeSH
- obvod pasu * MeSH
- referenční hodnoty MeSH
- rizikové faktory MeSH
- tělesná výška * MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Slovenská republika MeSH
The aim of our study was to evaluate the effects of the different probiotic strains, Lactobacillus plantarum LS/07 and Lactobacillus plantarum Biocenol LP96, on lipid metabolism and body weight in rats fed a high fat diet. Compared with the high fat diet group, the results showed that Lactobacillus plantarum LS/07 reduced serum cholesterol and LDL cholesterol, but Lactobacillus plantarum Biocenol LP96 decreased triglycerides and VLDL, while there was no change in the serum HDL level and liver lipids. Both probiotic strains lowered total bile acids in serum. Our strains have no significant change in body weight, gain weight, and body fat. These findings indicate that the effect of lactobacilli on lipid metabolism may differ among strains and that the Lactobacillus plantarum LS/07 and Lactobacillus plantarum Biocenol LP96 can be used to improve lipid profile and can contribute to a healthier bowel microbial balance.
- MeSH
- dieta s vysokým obsahem tuků * MeSH
- glukuronidasa metabolismus MeSH
- krysa rodu Rattus MeSH
- Lactobacillus plantarum enzymologie metabolismus MeSH
- lipidy krev MeSH
- metabolismus lipidů * MeSH
- probiotika aplikace a dávkování metabolismus MeSH
- tělesná hmotnost MeSH
- zvířata MeSH
- Check Tag
- krysa rodu Rattus MeSH
- mužské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- glukuronidasa MeSH
- lipidy MeSH
