Monitoring of body burden of toxic elements is usually based on analysis of concentration of particular elements in blood, urine and/or hair. Analysis of these matrices, however, predominantly reflects short- or medium-term exposure to trace elements or pollutants. In this work, urinary stones were investigated as a matrix for monitoring long-term exposure to toxic and essential elements. A total of 431 samples of urinary calculi were subjected to mineralogical and elemental analysis by infrared spectroscopy and inductively coupled plasma mass spectrometry. The effect of mineralogical composition of the stones and other parameters such as sex, age and geographical location on contents of trace and minor elements is presented. Our results demonstrate the applicability of such approach and confirm that the analysis of urinary calculi can be helpful in providing complementary information on human exposure to trace metals and their excretion. Analysis of whewellite stones (calcium oxalate monohydrate) with content of phosphorus <0.6 % has been proved to be a promising tool for biomonitoring of trace and minor elements.
- Klíčová slova
- Biomonitoring, Exposure, Trace elements, Urinary stones, Urolithiasis,
- MeSH
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- močové kameny chemie MeSH
- monitorování životního prostředí metody MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- sexuální faktory MeSH
- šťavelan vápenatý analýza MeSH
- stopové prvky analýza MeSH
- věkové faktory MeSH
- zeměpis MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
- Názvy látek
- šťavelan vápenatý MeSH
- stopové prvky MeSH
- whewellite MeSH Prohlížeč