The activity of succinate dehydrogenase (SDH) was examined histochemically in the parenchyma of murine submandibular gland (SMG) during postnatal development on light-microscopical level. In this study, SDH appears as a good marker of differentiating and mature striated ducts of both sexes and convoluted granular tubules of males. Enzyme activity in glandular parenchyma increased from the 1st day to the 7th week of postnatal life. Definitive enzymatic pattern was seen in the gland aged 7 weeks. Histochemical differences between male and female SMG of mouse were noted.

• MeSH
• histocytochemie MeSH
• myši MeSH
• podčelistní slinná žláza enzymologie   růst a vývoj   MeSH
• stárnutí metabolismus   MeSH
• sukcinátdehydrogenasa analýza   MeSH
• zvířata MeSH
• Check Tag
• mužské pohlaví MeSH
• myši MeSH
• ženské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• sukcinátdehydrogenasa MeSH

Histochemical localization of succinate dehydrogenase in developing intracerebral auto- and homotransplants of the mouse submandibular gland was investigated in the course of a 5-month period after transplantation. Eight weeks after grafting, the enzyme pattern in the parenchyma of homotransplants was comparable with the histochemical picture of a fully mature submandibular gland in situ. At this time, numerous acini showed a weak activity, very numerous striated ducts a strong activity, and less frequent developing convoluted granular tubules slightly weaker activity, than in the striated ducts. Beginning histochemical differentiation of convoluted granular tubules was noted only in homotransplants, located in the brain of male recipients. On the other hand, only a weak activity in the cytoplasm of non-differentiated duct--like structures of some autotransplants was seen. Homotransplants of non-differentiated submandibular gland of newborn donors were found to be a more suitable transplantation object capable of postnatal development of gland parenchyma than autografts of fully differentiated gland of adult animals that did not enter the cytodifferentiation stage.

• MeSH
• autologní transplantace MeSH
• histocytochemie MeSH
• homologní transplantace MeSH
• mozek chirurgie   MeSH
• myši MeSH
• podčelistní slinná žláza enzymologie   transplantace   MeSH
• sukcinátdehydrogenasa analýza   MeSH
• zvířata MeSH
• Check Tag
• mužské pohlaví MeSH
• myši MeSH
• ženské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• sukcinátdehydrogenasa MeSH

The localization of aminopeptidase M (APM), aminopeptidase A (APA) and gama-glutamyltransferase (GGT) activity was studied at light microscope level in the nasal cavity organs of the laboratory rodents (rat, mouse, guinea pig) and human foetuses. All the enzymes were demonstrated histochemically in chloroform-acetone pretreated cryostat sections with application of azocoupling methods (5, 9). These membrane-bound aminopeptidases may participate in the metabolism of peptides in the nasal cavity. They have specific roles as modulators of growth and differentiation of the epithelial cells. The results revealed differences in enzyme patterns between olfactory and respiratory epithelium. GGT seemed to be present only in respiratory epithelium and in the ducts of Bowman's glands. Activity of APM and APA was found mostly in the fibrocytes which adhered to the basal membrane of the epithelium and glands.

• MeSH
• aminopeptidasy analýza   MeSH
• antigeny CD13 analýza   MeSH
• gama-glutamyltransferasa analýza   MeSH
• glutamylaminopeptidasa MeSH
• histocytochemie MeSH
• krysa rodu Rattus MeSH
• lidé MeSH
• morčata MeSH
• myši MeSH
• nosní dutina enzymologie   MeSH
• plod enzymologie   MeSH
• zvířata MeSH
• Check Tag
• krysa rodu Rattus MeSH
• lidé MeSH
• morčata MeSH
• myši MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• aminopeptidasy MeSH
• antigeny CD13 MeSH
• gama-glutamyltransferasa MeSH
• glutamylaminopeptidasa MeSH

The localization of dipeptidylpeptidase IV (DPP IV) activity was studied at light microscope level in the mucosa, glands and capillary endothelium of the human foetuses and rat, mouse and guinea pig in some prenatal and postnatal terms. Alkaline phosphatase reaction was used for complete histochemical demonstration of capillary endothelium. The two enzymes were mapped by Lojda's methods (12). The study brings knowledge of the localization of DPP IV activity in the nasal cavity structures and gives a different time survey of the onset of DPP IV activity during ontogenesis. Considering this activity we can presume that this membrane-bound protease DPP IV may participate in the metabolism of neuropeptides in the nasal cavity and play some role in immunological disturbances of patients with rhinitis.

• MeSH
• cévní endotel enzymologie   MeSH
• dipeptidylpeptidasa 4 MeSH
• dipeptidylpeptidasy a tripeptidylpeptidasy analýza   MeSH
• histocytochemie MeSH
• krysa rodu Rattus MeSH
• lidé MeSH
• morčata MeSH
• myši MeSH
• nosní dutina krevní zásobení   enzymologie   MeSH
• plod enzymologie   MeSH
• zvířata MeSH
• Check Tag
• krysa rodu Rattus MeSH
• lidé MeSH
• morčata MeSH
• myši MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH
• Názvy látek
• dipeptidylpeptidasa 4 MeSH
• dipeptidylpeptidasy a tripeptidylpeptidasy MeSH

• MeSH
• miniaturní prasata anatomie a histologie   MeSH
• nervosvalová ploténka anatomie a histologie   MeSH
• nervosvalové spojení anatomie a histologie   MeSH
• prasata MeSH
• svaly inervace   MeSH
• zadní končetina anatomie a histologie   inervace   MeSH
• zvířata MeSH
• Check Tag
• zvířata MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH

• MeSH
• bérec * MeSH
• kur domácí anatomie a histologie   MeSH
• nervosvalová ploténka anatomie a histologie   MeSH
• nervosvalové spojení anatomie a histologie   MeSH
• svaly inervace   MeSH
• zvířata MeSH
• Check Tag
• mužské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• anglický abstrakt MeSH
• časopisecké články MeSH