Systematic strategies for preventing and treating esophagogastric variceal rebleeding (EVRB) are currently inadequate. This systematic review aimed to update this critical gap by searching contemporary studies from major guideline websites, databases, and professional associations focused on EVRB prevention in cirrhosis patients. Key findings highlight evaluation methods, risk management, preventive measures, health education, and follow-up strategies. Notably, a hepatic venous pressure gradient exceeding 18 mmHg is identified as a reliable predictor of gastroesophageal varices (GOV) rebleeding. Effective management of primary diseases is crucial, with methods including antiviral and anti-fibrotic therapies, alcohol avoidance, vaccination, and careful medication management. The combination of nonselective β-blockers (NSBBs) and endoscopic variceal ligation (EVL) is established as the gold standard for secondary EVRB prevention. For patients experiencing recurrent bleeding despite NSBBs and EVL, transjugular intrahepatic portosystemic shunt (TIPS) therapy is recommended. Surgical options, such as surgical shunt and devascularization, are advised for those unsuitable for endoscopic therapy or TIPS, particularly in Child-Pugh A and B patients unresponsive to treatment. Additionally, traditional Chinese medicine options, such as Fufang Biejia Ruangan Tablets, Fuzheng Huayu Capsules, and Anluo Huaxian Pills, have shown promise in improving hepatic fibrosis and GOV in cirrhotic patients. This review offers a comprehensive overview of current prevention and treatment strategies for EVRB, providing valuable insights for clinicians and healthcare professionals.
- Klíčová slova
- esophagogastric varices, evidence-based nursing, liver cirrhosis, prevention, rebleeding,
- MeSH
- ezofageální a žaludeční varixy * komplikace MeSH
- gastrointestinální krvácení * etiologie prevence a kontrola MeSH
- jaterní cirhóza * komplikace MeSH
- lidé MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- systematický přehled MeSH
Low-temperature combustion synthesis was utilized to prepare Co-Ni-W-based oxide dispersion strengthened (ODS) alloy powder. The influence of the U/Co and C/Co ratios on the morphology and specific surface area of the combusted powder was investigated. Particle size, phase constituents, and element distribution of the resulting Co-Ni-W-based ODS alloy powder were characterized. The results indicate that insufficient urea induced no autocombustion reaction, while excess urea and glucose inhibited the combustion reaction. The optimized contents of urea and glucose were around U/Co = 1.2 and C/Co = 1.5, and the specific surface area of the powder reached 43.5 m²/g. The lamellar Co-Ni-W-based ODS alloy powder with particle sizes of 1-21 μm was the soft agglomeration of a high population of nanosized (65 nm) particles. These nanoparticles grew from 65 to 260 nm in the reduction temperature range of 700-900 °C. Homogeneous distribution of Co, Ni, W, and Y in the Co-Ni-W-based ODS alloy powder was achieved.
- Klíčová slova
- Co-Ni-W-based powder, low-temperature combustion synthesis, oxide dispersion strengthening, particle size,
- Publikační typ
- časopisecké články MeSH
