The use of cannabis for medical purposes has been recently legalised in many countries including the Czech Republic. As a result, there is increased interest on the part of physicians and patients in many aspects of its application. This mini review briefly covers the main active substances of the cannabis plant and mechanisms of action. It focuses on two conditions, cancer pain and spasticity in multiple sclerosis, where its effects are well-documented. A comprehensive overview of a few cannabis-based products and the basic pharmacokinetics of marijuana's constituents follows. The review concludes with an outline for preparing cannabis (dried inflorescence) containing drug dosage forms that can be produced in a hospital pharmacy.
- Klíčová slova
- THC, cancer, cannabinoids, cannabis, mechanism of action, multiple sclerosis, pain, spasms,
- MeSH
- fytoterapie MeSH
- kanabinoidy aplikace a dávkování farmakologie MeSH
- lidé MeSH
- marihuana pro léčebné účely aplikace a dávkování farmakologie MeSH
- nádorová bolest farmakoterapie MeSH
- opioidní analgetika aplikace a dávkování farmakologie MeSH
- rostlinné přípravky MeSH
- svalová spasticita farmakoterapie MeSH
- způsoby aplikace léků MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
- Názvy látek
- kanabinoidy MeSH
- marihuana pro léčebné účely MeSH
- opioidní analgetika MeSH
- rostlinné přípravky MeSH
