In this study, we characterized a collection of clinical samples obtained from Syrian and Turkish patients with cutaneous leishmaniasis using internal transcribed spacer 1 (ITS1) sequences. All obtained sequences belonged to Leishmania tropica. Combining them with those available from GenBank allowed us performing a broad-scale analysis of genetic diversity for this species. We demonstrated that L. tropica has a complex phylogeographic pattern with some haplotypes being widespread across endemic countries and others restricted to particular regions. We hypothesize that at least some of them may be associated with alternative vectors or animal reservoirs.

• Klíčová slova
• Cutaneous leishmaniasis, Haplotype diversity, ITS1, Phylogeography,
• MeSH
• fylogeografie MeSH
• genetická variace * MeSH
• haplotypy MeSH
• infekce přenášené vektorem MeSH
• Leishmania tropica genetika   MeSH
• leishmanióza kožní epidemiologie   přenos   MeSH
• lidé MeSH
• zvířata MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• zvířata MeSH
• Publikační typ
• časopisecké články MeSH