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Autor
Adorjan, Kristina 1 Alda, Martin 1 Andlauer, Till F M 1 Ardau, Raffaela 1 Aubry, Jean-Michel 1 Brosch, Katharina 1 Budde, Monika 1 Chillotti, Caterina 1 Czerski, Piotr M 1 Dannlowski, Udo 1 DePaulo, Raymond J 1 Falkai, Peter 1 Forstner, Andreas 1 Goes, Fernando S 1 Grigoroiu-Serbanescu, Maria 1 Grof, Paul 1 Grotegerd, Dominik 1 Hahn, Tim 1 Hasler, Roland 1 Heilbronner, Maria 1
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Center for Mind Brain and Behavior Un... 1 Centre for Human Genetics University ... 1 Centro de Investigación Biomedica en ... 1 Department of Biomedical Sciences Uni... 1 Department of Genetic Epidemiology in... 1 Department of Immunology School of Me... 1 Department of Neurology Klinikum Rech... 1 Department of Psychiatric Genetics Po... 1 Department of Psychiatry Dalhousie Un... 1 Department of Psychiatry Geneva Unive... 1 Department of Psychiatry University o... 1 Department of Psychiatry University o... 1 Department of Psychiatry and Behavior... 1 Department of Psychiatry and Behavior... 1 Department of Psychiatry and Behavior... 1 Department of Psychiatry and Psychoth... 1 Department of Psychiatry and Psychoth... 1 Faculty of Medicine University of Gen... 1 Global Computational Biology and Data... 1 Institute for Translational Neuroscie... 1
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Autor
Adorjan, Kristina 1 Alda, Martin 1 Andlauer, Till F M 1 Ardau, Raffaela 1 Aubry, Jean-Michel 1 Brosch, Katharina 1 Budde, Monika 1 Chillotti, Caterina 1 Czerski, Piotr M 1 Dannlowski, Udo 1 DePaulo, Raymond J 1 Falkai, Peter 1 Forstner, Andreas 1 Goes, Fernando S 1 Grigoroiu-Serbanescu, Maria 1 Grof, Paul 1 Grotegerd, Dominik 1 Hahn, Tim 1 Hasler, Roland 1 Heilbronner, Maria 1
- Organizace
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Pracoviště
Center for Mind Brain and Behavior Un... 1 Centre for Human Genetics University ... 1 Centro de Investigación Biomedica en ... 1 Department of Biomedical Sciences Uni... 1 Department of Genetic Epidemiology in... 1 Department of Immunology School of Me... 1 Department of Neurology Klinikum Rech... 1 Department of Psychiatric Genetics Po... 1 Department of Psychiatry Dalhousie Un... 1 Department of Psychiatry Geneva Unive... 1 Department of Psychiatry University o... 1 Department of Psychiatry University o... 1 Department of Psychiatry and Behavior... 1 Department of Psychiatry and Behavior... 1 Department of Psychiatry and Behavior... 1 Department of Psychiatry and Psychoth... 1 Department of Psychiatry and Psychoth... 1 Faculty of Medicine University of Gen... 1 Global Computational Biology and Data... 1 Institute for Translational Neuroscie... 1
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Kalman, Janos L
Autor Kalman, Janos L ORCID Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Nussbaumstr. 7, 80336, Munich, Germany. janos.kalman@med.uni-muenchen.de Department of Psychiatry and Psychotherapy, University Hospital Munich, Munich, Germany. janos.kalman@med.uni-muenchen.de International Max Planck Research School for Translational Psychiatry, Munich, Germany. janos.kalman@med.uni-muenchen.de
- Yoshida, Tomoya
- Andlauer, Till F M
- Schulte, Eva C
- Adorjan, Kristina
- Alda, Martin
- Ardau, Raffaela
- Aubry, Jean-Michel
- Brosch, Katharina
- Budde, Monika
PubMed
35146571
PubMed Central
PMC9653330
DOI
10.1007/s00406-021-01366-5
PII: 10.1007/s00406-021-01366-5
Knihovny.cz E-zdroje
Personality traits influence risk for suicidal behavior. We examined phenotype- and genotype-level associations between the Big Five personality traits and suicidal ideation and attempt in major depressive, bipolar and schizoaffective disorder, and schizophrenia patients (N = 3012) using fixed- and random-effects inverse variance-weighted meta-analyses. Suicidal ideations were more likely to be reported by patients with higher neuroticism and lower extraversion phenotypic scores, but showed no significant association with polygenic load for these personality traits. Our findings provide new insights into the association between personality and suicidal behavior across mental illnesses and suggest that the genetic component of personality traits is unlikely to have strong causal effects on suicidal behavior.
- Klíčová slova
- Bipolar disorder, Major depression, Personality, Polygenic score, Schizophrenia, Suicidal behavior,
- MeSH
- depresivní porucha unipolární * psychologie MeSH
- duševní zdraví MeSH
- fenotyp MeSH
- lidé MeSH
- osobnost genetika MeSH
- sebevražedné myšlenky * MeSH
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- lidé MeSH
- Publikační typ
- časopisecké články MeSH
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